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Table 1 Clinical and sociodemographic characteristics of patients with and without on target LDL-C levels

From: Utilization of statins and LDL-cholesterol target attainment in Turkish patients with type 2 diabetes - a nationwide cross-sectional study (TEMD dyslipidemia study)

Variables Total Patients
(n = 4504)
Patients with LDL-C on target
(n = 922, 20.5%)
Patients with LDL-C not on target
(n = 3582, 79.5%)
p
Gender (Female n,%) 2639 (58.6) 475 (51.5) 2164 (60.4) < 0.001
Age (year) 58.6 ± 10.4 58.4 (±10.5) 58.6 (±10.4) 0.68
BMI (kg/m2) 32.1 ± 6.5 31.8 (±6.6) 32.1 (±6.4) 0.12
SBP (mmHg) 132.5 ± 18.3 131.4 (±18.1) 132.8 (±18.4) 0.03
DBP (mmHg) 80.5 ± 10.7 80.0 (±10.7) 80.6 (±10.7) 0.17
Diabetes duration (year) 10.9 ± 7.5 10.8 (±7.4) 11.0 (±7.5) 0.46
Active smoking (n,%) 561 (12.5) 119 (13.0) 442 (12.4) 0.61
HbA1c (%) 7.73 ± 1.74 7.60 (±1.64) 7.75 (±1.77) 0.015
HbA1c levels < 7% 1790 (40.2) 390 (42.7) 1400 (39.5) 0.085
Exercise (n,%) 883 (19.6) 226 (24.7) 657 (18.6) < 0.001
Higher education (n,%) 1722 (38.2) 369 (40.4) 1353 (38.4) 0.26
Private center follow-up (n,%) 483 (10.2) 123 (13.3) 342 (9.5) 0.001
Microvascular complications (n,%) 2142 (47.6) 222 (24.1) 1920 (53.6) < 0.001
 Retinopathy (n,%) 874 (21.3) 107 (12.5) 767 (23.7) < 0.001
 Nephropathy (n,%) 817 (19.6) 84 (9.7) 733 (22.2) < 0.001
 Neuropathy (n,%) 1545 (34.7) 163 (17.9) 1382 (39.0) < 0.001
Macrovascular complications (n,%) 1103 (24.5) 165 (17.9) 938 (26.2) < 0.001
 Coronary artery disease (n,%) 962 (21.4) 151 (17.7) 811 (24.5) < 0.001
 Peripheral artery disease (n,%) 175 (4.2) 28 (3.2) 147 (4.4) 0.11
 Cerebrovascular disease (n,%) 132 (3.0) 19 (2.1) 113 (3.3) 0.07
Obesity (n,%) 2593 (58.3) 472 (51.7) 2027 (56.8) 0.005
Hypertension (n,%) 3074 (68.6) 621 (67.8) 2453 (68.8) 0.58
 Blood pressure on target (n,%) 3128 (69.9) 668 (73.1) 2460 (69.1) 0.020
LDL-Cholesterol (mg/dl) 113.9 (±36.2) 73.8 (±17.1) 124.2 (±32.4) < 0.001
HDL-Cholesterol (mg/dl) 46.5 (±12.9) 45.5 (±14.7) 46.9 (±12.4) 0.005
 HDL- Cholesterol on target (n,%) 1978 (43.9) 376 (41.8) 1602 (46.8) 0.007
Triglycerides (mg/dl) 182.1 (±128.7) 164.0 (±113.7) 181.4 (±115.8) < 0.001
 Triglycerides on target (n,%) 2272 (50.4) 529 (57.8) 1743 (48.8) < 0.001
Statin treatment (n,%) 1807 (40.1) 448 (48.6) 1359 (37.9) < 0.001
 High intensity statin (n,%) 181 (4.0) 41 (22.7) 140 (77.3) 0.48
  1. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HbA1c glycosylated hemoglobin, LDL low-density lipoprotein, HDL high-density lipoprotein, Data are expressed as (mean ± SD) number (%) where appropriate
  2. p-values are derived from Student’s t-test and Chi-square tests for continuous and categorical variables, respectively