Exposure | Model 1 | P value | Model 2 | P value | Model 3 | P value |
---|---|---|---|---|---|---|
Hazard ratio (95% CI) | Hazard ratio (95% CI) | Hazard ratio (95% CI) | ||||
Female | ||||||
 TyG-BMI (1-SD increase) | 4.170 (3.692, 4.709) | < 0.001 | 4.166 (3.688, 4.705) | < 0.001 | 3.583 (2.796, 4.593) | < 0.001 |
TyG-BMI Quartile | ||||||
 Q1 | 1 |  | 1 |  | 1 |  |
 Q2 | 3.237 (1.186, 8.836) | 0.022 | 3.237 (1.186, 8.836) | 0.022 | 3.164 (0.669, 14.958) | 0.146 |
 Q3 | 19.206 (7.800, 47.293) | < 0.001 | 19.200 (7.797, 47.279) | < 0.001 | 10.716 (2.566, 44.744) | 0.001 |
 Q4 | 77.980 (32.206, 188.810) | < 0.001 | 77.920 (32.173, 188.713) | < 0.001 | 30.978 (7.427, 129.208) | < 0.001 |
P for trend | 5.689 (4.762, 6.797) | < 0.001 | 5.687 (4.759, 6.797) | < 0.001 | 3.648 (2.733, 4.870) | < 0.001 |
Male | ||||||
 TyG-BMI (1-SD increase) | 3.954 (3.513, 4.451) | < 0.001 | 3.945 (3.504, 4.440) | < 0.001 | 2.849 (2.298, 3.532) |  |
TyG-BMI Quartile | ||||||
 Q1 | 1 |  | 1 |  | 1 |  |
 Q2 | 9.985 (2.326, 42.868) | 0.002 | 9.964 (2.321, 42.778) | 0.002 | 8.338 (1.057, 65.749) | 0.044 |
 Q3 | 49.743 (12.264, 201.752) | < 0.001 | 49.323 (12.160, 200.065) | < 0.001 | 24.649 (3.369, 180.346) | 0.002 |
 Q4 | 171.006 (42.585, 686.699) | < 0.001 | 169.762 (42.273, 681.737) | < 0.001 | 56.284 (7.712, 410.750) | < 0.001 |
P for trend | 5.098 (4.298, 6.047) | < 0.001 | 5.090 (4.291, 6.038) | < 0.001 | 3.098 (2.387, 4.020) | < 0.001 |
Total | ||||||
TyG-BMI (1-SD increase) | 4.053 (3.724, 4.412) | < 0.001 | 4.046 (3.717, 4.405) | < 0.001 | 3.089 (2.628, 3.631) | < 0.001 |
TyG-BMI Quartile | ||||||
 Q1 | 1 |  | 1 |  | 1 |  |
 Q2 | 5.164 (2.294, 11.626) | < 0.001 | 5.161 (2.292, 11.618) | < 0.001 | 4.718 (1.387, 16.040) | 0.013 |
 Q3 | 27.953 (13.142, 59.456) | < 0.001 | 27.832 (13.085, 59.202) | < 0.001 | 15.062 (4.743, 47.835) | < 0.001 |
 Q4 | 104.387 (49.549, 219.914) | < 0.001 | 103.788 (49.261, 218.670) | < 0.001 | 38.242 (12.065, 121.213) | < 0.001 |
P for trend | 5.387 (4.762, 6.094) | < 0.001 | 5.373 (4.749, 6.079) | < 0.001 | 3.336 (2.750, 4.047) | < 0.001 |