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Table 4 The hazard ratio (95% CI) of Hyper-CEA for MetS in subcohort A by stratified analysis

From: Bidirectional association between serum carcinoembryonic antigen and metabolic syndrome among the Chinese male population: two cohort studies

Characteristics

Model 1a

Model 2b

β

Hazard ratio (95% CI)

P

β

Hazard ratio (95% CI)

P

Age ≤ 45 y, nonsmoking (n = 2498)

 Hyper-CEA

0.134

1.14 (0.69, 1.91)

0.607

−0.005

0.99 (0.58, 1.7)

0.985

 Norm-CEA

 

1

  

1

 

Age > 45 y and ≤ 65 y, nonsmoking(n = 1107)

 Hyper-CEA

−0.363

0.70 (0.41, 1.18)

0.18

−0.392

0.68 (0.39, 1.17)

0.161

 Norm-CEA

 

1

  

1

 

Age > 65 y, nonsmoking (n = 335)

 Hyper-CEA

−0.103

0.90 (0.46, 1.79)

0.768

−0.063

0.94 (0.45, 1.95)

0.867

 Norm-CEA

 

1

  

1

 

Age ≤ 45 y, smoking (n = 1527)

 Hyper-CEA

−0.169

0.84 (0.49, 1.46)

0.543

−0.223

0.8 (0.45, 1.42)

0.447

 Norm-CEA

 

1

  

1

 

Age > 45 y and ≤ 65 y, smoking (n = 855)

 Hyper-CEA

−0.185

0.83 (0.56, 1.23)

0.35

−0.019

0.98 (0.64, 1.51)

0.93

 Norm-CEA

 

1

  

1

 

Age > 65 y, smoking (n = 86)

 Hyper-CEA

−0.58

0.56 (0.12, 2.54)

0.452

0.128

1.14 (0.15, 8.66)

0.902

 Norm-CEA

 

1

  

1

 
  1. a: Model 1 was the unadjusted hazard ratio; b: Model 2 was adjusted for alcohol intake, the components of MetS, blood uric acid, alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transpeptidase, haemoglobin and white blood cell count. CEA Carcinoembryonic antigen; Hyper-CEA Elevated serum CEA level above the reference range; Norm-CEA Within the normal reference ranges; MetS Metabolic syndrome