Association between statin use and osteoporotic fracture in patients with chronic obstructive pulmonary disease: a population-based, matched case-control study

Table 2 Incidence of hazard ratios (HRs) with 95% confidence intervals (CIs) for new-onset osteoporotic fracture in statin-treated patient COPD compared with statin non-user COPD subjects

	Crude β (95% CI)	Crude HR (95% CI)	P value	Adjusted β^a (95% CI)	Adjusted HR^a(95% CI)	P value
COPD without statin-treated	ref	ref		ref	ref
COPD in statin-treated	0.113 (0.010 to 0.223)	1.12 (1.01–1.25)	0.032	−0.211 (−0.598 to 0.191)	0.81 (0.55–1.21)	0.584

^a(β and HR) were adjusted for age, sex, hypertension, CAD, CHF, CKD, DM, dementia, cancer, hyperthyroidism, obesity, depression, rheumatic arthritis, alcoholism and concurrent medication

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