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Table 2 Association between the LDL-C/HDL-C ratio and all-cause mortality during the follow-up period

From: A U-shaped association between the LDL-cholesterol to HDL-cholesterol ratio and all-cause mortality in elderly hypertensive patients: a prospective cohort study

LDL-C/HDL-C ratio

Events, %

Crude model

Model 1

Model 2

HR (95% CI) a

P value

HR (95% CI)

P value

HR (95% CI)

P value

Continuous

157/6947 (2.29)

0.93 (0.73, 1.19)

0.558

1.05 (0.83, 1.34)

0.674

1.02 (0.76, 1.36)

0.912

Quintiles

  < 1.16

40/1387 (2.88)

2.12 (1.23, 3.67)

0.007

1.88 (1.09, 3.25)

0.024

1.98 (1.13, 3.46)

0.017

 1.16–1.67

32/1389 (2.30)

1.69 (0.96, 2.98)

0.070

1.57 (0.89, 2.78)

0.118

1.64 (0.92, 2.90)

0.091

 1.67–2.10

19/1389 (1.37)

Reference

 

Reference

 

Reference

 

 2.10–2.79

30/1387 (2.16)

1.59 (0.89, 2.82)

0.115

1.75 (0.98, 3.11)

0.057

1.80 (1.01, 3.22)

0.048

  ≥ 2.79

36/1389 (2.59)

1.91 (1.09, 3.33)

0.023

2.12 (1.21, 3.70)

0.008

2.24 (1.24, 4.03)

0.008

Categories

  < 1.67

72/2776 (2.59)

1.91 (1.15, 3.16)

0.012

1.73 (1.04, 2.87)

0.034

1.81 (1.08, 3.03)

0.024

 1.67–2.10

19/1389 (1.37)

Reference

 

Reference

 

Reference

 

  ≥ 2.10

66/2776 (2.38)

1.75 (1.05, 2.91)

0.032

1.93 (1.16, 3.23)

0.011

2.00 (1.18, 3.39)

0.010

P for trend

 

0.570

0.598

0.767

  1. a Cox proportional hazards models were used to estimate hazard ratio (HR) and 95% confidence interval (95% CI)
  2. Abbreviations: HR hazard ratio; CI confidence interval; LDL-C low density lipoprotein-cholesterol; HDL-C high-density lipoprotein cholesterol
  3. Model 1: adjusted for none. Model 2: adjusted for age, sex. Model 3: adjuste d for age, sex, BMI, SBP, DBP, TG, Hcy, FBG, SUA, eGFR, smoking, alcohol consumption, diabetes, stroke, CVD and anti-hypertensive drugs