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Table 3 The subgroup analysis for the LDL-C/HDL-C ratio on all-cause mortality

From: A U-shaped association between the LDL-cholesterol to HDL-cholesterol ratio and all-cause mortality in elderly hypertensive patients: a prospective cohort study

Subgroups

Categories of the LDL-C/HDL-C ratio, HR (95% CI)

 

P for interaction

Low (< 1.67)

Reference (1.67–2.10)

High (≥2.10)

Sex

   

0.249

 male

1.38 (0.76, 2.50)

1

1.51 (0.80, 2.84)

 

 female

3.33 (1.15, 9.69)

1

3.92 (1.35, 11.36)

 

BMI, kg/m2

   

0.99

  < 24

1.81 (1.01, 3.26)

1

2.13 (1.14, 3.98)

 

  ≥ 24

1.85 (0.62, 5.50)

1

1.73 (0.64, 4.70)

 

Stroke

   

0.623

 No

1.71 (1.00, 2.91)

1

1.81 (1.05, 3.14)

 

 Yes

3.63 (0.40, 32.93)

1

6.89 (0.79, 60.40)

 

CVD

   

0.21

 No

1.58 (0.93, 2.69)

1

2.01 (1.17, 3.45)

 

 Yes

4.23 (0.43, 41.60)

1

1.38 (0.10, 18.38)

 

Diabetes

   

0.25

 No

1.63 (0.95, 2.79)

1

1.68 (0.96, 2.94)

 

 Yes

6.38 (0.80, 50.66)

1

8.18 (1.04, 64.02)

 

eGFR, ml/min/1.73m2

   

0.097

  < 60

5.35 (1.24, 23.09)

1

8.93 (2.02, 39.51)

 

  ≥ 60

1.45 (0.82, 2.55)

1

1.44 (0.80, 2.57)

 

Smoking

   

0.452

 No

2.10 (1.16, 3.80)

1

2.07 (1.12, 3.82)

 

 Yes

1.12 (0.40, 3.18)

1

1.86 (0.64, 5.37)

 

Alcohol consumption

   

0.969

 No

1.75 (1.01, 3.03)

1

1.99 (1.13, 3.48)

 

 Yes

1.87 (0.40, 8.68)

1

1.91 (0.38, 9.68)

 
  1. Adjusted for age, sex, BMI, SBP, DBP, TG, Hcy, FBG, SUA, eGFR, smoking, alcohol consumption, diabetes, stroke, CVD and anti-hypertensive drugs, if not be stratified