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Table 2 Association between TyG index and LSMI

From: Inverse association between triglyceride glucose index and muscle mass in Korean adults: 2008–2011 KNHANES

TyG index tertile

Sample size of LSMI, n (%)

B

SE

ORs

95% CIs

Wald

p

Overall p

p for trend

Unadjusted

     

79.670

 

< 0.001

< 0.001

 T1

228 (4.4)

Ref.

Ref.

1 (Ref.)

Ref.

 

Ref.

  

 T2

446 (8.5)

0.799

79.67

2.223

1.781–2.776

 

< 0.001

  

 T3

712 (13.5)

1.267

0.103

3.549

2.897–4.347

 

< 0.001

  

Model 1

     

28.277

 

< 0.001

< 0.001

 T1

228 (4.4)

Ref.

Ref.

1 (Ref.)

Ref.

 

Ref.

  

 T2

446 (8.5)

0.482

0.121

1.619

1.277–2.053

 

< 0.001

  

 T3

712 (13.5)

0.831

0.116

2.296

1.829–2.881

 

< 0.001

  

Model 2

     

14.880

 

< 0.001

< 0.001

 T1

228 (4.4)

Ref.

Ref.

1 (Ref.)

Ref.

 

Ref.

  

 T2

446 (8.5)

0.434

0.130

1.544

1.195–1.994

 

0.001

  

 T3

712 (13.5)

0.711

0.133

2.037

1.569–2.645

 

< 0.001

  

Model 3

     

10.809

 

< 0.001

< 0.001

 T1

228 (4.4)

Ref.

Ref.

1 (Ref.)

Ref.

 

Ref.

  

 T2

446 (8.5)

0.399

0.131

1.491

1.152–1.930

 

0.002

  

 T3

712 (13.5)

0.629

0.137

1.876

1.434–2.454

 

< 0.001

  

Model 4

     

10.013

 

< 0.001

< 0.001

 T1

228 (4.4)

Ref.

Ref.

1 (Ref.)

Ref.

 

Ref.

  

 T2

446 (8.5)

0.380

0.131

1.463

1.131–1.892

 

0.004

  

 T3

712 (13.5)

0.597

0.135

1.816

1.394–2.366

 

< 0.001

  
  1. Abbreviations: TyG index triglyceride-glucose index, LSMI low skeletal muscle mass index, ORs odds ratio, CIs confidence intervals
  2. Model 1: Adjusted for age, sex, body weight, and regular exercise.
  3. Model 2: Adjusted for variables included in Model 1 plus employment status, alcohol use, smoking status, daily protein intake, number of chronic diseases, and serum total cholesterol level.
  4. Model 3: Adjusted for variables included in Model 2 plus plasma glucose level.
  5. Model 4: Adjusted for variables included in Model 3 plus mean blood pressure./
  6. SMI was defined using the following equation: ASM (kg)/BMI (kg/m2).
  7. We defined the LSMI according to the cut-off value of SMI based on the Foundation for the National Institutes of Health (FNIH) sarcopenia project criteria: SMI less than 0.789 for men and SMI less than 0.512 for women.
  8. The odds ratio and 95% confidence interval were calculated using the weighted multi-variate logistic regression analysis to evaluate the relationship between TyG index and LSMI.
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Lipids in Health and Disease

ISSN: 1476-511X