ALT/AST ratio | Quintile 1 (< 0.6) | Quintile 2 (≥0.6, < 0.71) | Quintile 3 (≥0.71, < 0.84) | Quintile 4 (≥0.84, < 1.04) | Quintile 5 (≥1.04) | P-value |
---|---|---|---|---|---|---|
N (%) | 2387 (19.68%) | 2428 (20.02%) | 2374 (19.58%) | 2512 (20.71%) | 2426 (20.01%) | Â |
Clinical data | ||||||
 Age, years | 41.00 (32.00–54.00) | 40.00 (32.00–51.00) | 41.00 (32.00–53.00) | 40.00 (31.00–51.00) | 39.00 (31.00–50.00) | < 0.001 |
 Sex |  |  |  |  |  | < 0.001 |
  Female | 1123 (47.05%) | 1153 (47.49%) | 1104 (46.50%) | 1076 (42.83%) | 1025 (42.25%) |  |
  Male | 1264 (52.95%) | 1275 (52.51%) | 1270 (53.50%) | 1436 (57.17%) | 1401 (57.75%) |  |
 NAFLD | 136 (5.70%) | 233 (9.60%) | 330 (13.90%) | 580 (23.09%) | 868 (35.78%) | < 0.001 |
 Weight, kg | 56.22 ± 8.06 | 57.59 ± 8.03 | 59.23 ± 8.05 | 61.91 ± 8.04 | 64.48 ± 7.82 | < 0.001 |
 Height, m | 1.64 ± 0.08 | 1.65 ± 0.08 | 1.66 ± 0.08 | 1.67 ± 0.07 | 1.69 ± 0.07 | < 0.001 |
 BMI, kg/m2 | 20.80 (19.31–22.26) | 21.26 (19.70–22.78) | 21.71 (20.08–23.05) | 22.22 (20.67–23.58) | 22.80 (21.46–23.91) | < 0.001 |
 SBP, mmHg | 122.63 ± 19.05 | 121.17 ± 17.92 | 121.69 ± 16.76 | 122.94 ± 15.67 | 123.57 ± 14.94 | < 0.001 |
 DBP, mmHg | 72.00 (65.00–80.00) | 71.00 (65.00–79.00) | 73.00 (66.00–80.00) | 74.00 (67.00–81.00) | 74.00 (68.00–82.00) | < 0.001 |
Laboratory data | ||||||
 ALP, U/L | 68.70 ± 24.64 | 69.12 ± 20.28 | 70.94 ± 22.24 | 74.32 ± 23.29 | 78.52 ± 23.98 | < 0.001 |
 GGT, U/L | 18.00 (14.00–23.00) | 19.00 (15.00–24.00) | 21.00 (17.00–28.00) | 24.00 (19.00–34.00) | 32.00 (23.00–51.00) | < 0.001 |
 ALT, U/L | 10.00 (9.00–12.00) | 13.00 (11.00–15.00) | 16.00 (14.00–19.00) | 20.00 (17.00–24.00) | 31.00 (24.00–41.00) | < 0.001 |
 AST, U/L | 20.00 (18.00–24.00) | 20.00 (17.00–23.00) | 21.00 (18.00–24.00) | 22.00 (19.00–25.00) | 24.00 (21.00–30.00) | < 0.001 |
 TP, g/L | 73.86 ± 4.40 | 73.74 ± 4.11 | 73.61 ± 4.17 | 73.90 ± 4.23 | 74.16 ± 4.34 | < 0.001 |
 ALB, g/L | 44.18 ± 2.80 | 44.29 ± 2.79 | 44.42 ± 2.61 | 44.76 ± 2.81 | 45.05 ± 2.74 | < 0.001 |
 GLB, g/L | 29.68 ± 4.15 | 29.45 ± 3.94 | 29.19 ± 3.81 | 29.14 ± 3.82 | 29.11 ± 4.13 | < 0.001 |
 TB, μmol/L | 11.00 (8.70–14.40) | 11.30 (8.60–14.20) | 11.20 (8.90–14.60) | 11.60 (9.00–14.60) | 11.60 (9.20–14.90) | 0.003 |
 DBIL, μmol/L | 2.00 (1.50–2.90) | 2.00 (1.40–2.60) | 2.00 (1.40–2.60) | 1.90 (1.40–2.60) | 1.90 (1.40–2.60) | < 0.001 |
 BUN, mmol/L | 4.76 ± 1.63 | 4.56 ± 1.53 | 4.53 ± 1.39 | 4.58 ± 1.25 | 4.50 ± 1.20 | < 0.001 |
 CR, mmol/L | 78.00 (68.00–93.00) | 77.00 (67.00–92.00) | 80.00 (68.00–94.00) | 84.00 (72.00–95.00) | 87.00 (76.00–96.00) | < 0.001 |
 UA, μmol/L | 284.90 ± 94.09 | 275.54 ± 89.22 | 284.15 ± 88.02 | 304.56 ± 86.09 | 317.18 ± 83.47 | < 0.001 |
 FPG, mmol/L | 5.12 ± 0.65 | 5.16 ± 0.74 | 5.24 ± 0.82 | 5.27 ± 0.87 | 5.28 ± 1.03 | < 0.001 |
 TC, mmol/L | 4.58 ± 0.75 | 4.57 ± 0.72 | 4.61 ± 0.74 | 4.62 ± 0.77 | 4.66 ± 0.74 | < 0.001 |
 TG, mmol/L | 0.99 (0.77–1.35) | 1.02 (0.79–1.40) | 1.11 (0.84–1.54) | 1.23 (0.92–1.75) | 1.40 (1.02–2.02) | < 0.001 |
 HDL-C, mmol/L | 1.53 ± 0.37 | 1.51 ± 0.35 | 1.48 ± 0.36 | 1.40 ± 0.34 | 1.33 ± 0.34 | < 0.001 |
 LDL-C, mmol/L | 2.23 (1.89–2.56) | 2.24 (1.91–2.57) | 2.30 (1.95–2.63) | 2.32 (1.96–2.66) | 2.40 (2.05–2.71) | < 0.001 |