Association between the alanine aminotransferase/aspartate aminotransferase ratio and new-onset non-alcoholic fatty liver disease in a nonobese Chinese population: a population-based longitudinal study

Table 4 The result of the two-piecewise linear regression model

	β	(aHRs,95%CI)	P-value
Total
Fitting model by standard linear regression	0.74	2.09 (1.78, 2.46)	< 0.001
Fitting model by two-piecewise linear regression
The inflection point of ALT/AST ratio		0.93
≤ 0.93	2.67	14.41 (8.91, 23.30)	< 0.001
> 0.93	0.01	1.01 (0.78, 1.30)	0.939
Male
Fitting model by standard linear regression	0.71	2.02 (1.60, 2.56)	< 0.001
Fitting model by two-piecewise linear regression
The inflection point of ALT/AST ratio		1.22
≤ 1.22	1.48	4.39 (2.97, 6.49)	< 0.001
> 1.22	−0.42	0.65 (0.37, 1.15)	0.143
Female
Fitting model by standard linear regression	0.70	2.01 (1.60, 2.54)	< 0.001
Fitting model by two-piecewise linear regression
The inflection point of ALT/AST ratio		0.89
≤0.89	3.47	32.01 (14.18, 72.25)	< 0.001
> 0.89	−0.19	0.83 (0.57, 1.21)	0.326

Adjust for: sex, age, GGT, ALB, GLB, TB, DBIL, SBP, DBP, ALP, BUN, CR, UA, FPG, TG, HDL-C, LDL-C, height and BMI

ISSN: 1476-511X