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Table 1 Baseline characteristics of participants

From: Association between the non-HDL-cholesterol to HDL-cholesterol ratio and non-alcoholic fatty liver disease in Chinese children and adolescents: a large single-center cross-sectional study

Characteristics NHDLC/HDLC ratio P value
Tertile 1 Tertile 2 Tertile 3
(≤ 1.79) (1.80–2.36) (≥ 2.37)
Sample size 2577 2580 2602  
Age (year) 9.24 ± 3.11 9.00 ± 3.31b 9.03 ± 3.47 0.017
Sex, n (%)     < 0.001
 Girl 771 (29.92) 950 (36.82)b 906 (34.82)a  
 Boy 1806 (70.08) 1630 (63.18)b 1696 (65.18)a  
BMI (kg/m2) 16.47 ± 2.64 17.02 ± 3.27b 18.64 ± 4.60a/c < 0.001
ALT (U/L) 15.12 ± 8.49 15.93 ± 17.55 19.27 ± 19.88a/c < 0.001
AST (U/L) 26.51 ± 6.75 26.64 ± 13.29 27.09 ± 13.62 0.175
ALP (U/L) 252.60 ± 78.46 242.84 ± 71.71b 240.50 ± 76.05a < 0.001
GGT (U/L) 12.29 ± 5.27 12.83 ± 6.02b 15.45 ± 9.98a/c < 0.001
TB (mmol/L) 9.88 ± 4.38 9.66 ± 4.36 9.27 ± 4.14ac < 0.001
Cr (μmol/L) 39.50 ± 8.75 39.31 ± 9.48 39.35 ± 10.24 0.749
UA (μmol/L) 300.55 ± 69.92 305.06 ± 73.84 327.42 ± 85.44a/c < 0.001
ALB (g/L) 45.36 ± 2.22 45.48 ± 2.17 45.78 ± 2.33a/c < 0.001
TC (mmol/L) 4.09 ± 0.63 4.27 ± 0.65b 4.62 ± 0.82a/c < 0.001
TG (mmol/L) 0.77 ± 0.30 0.89 ± 0.36b 1.21 ± 0.64a/c < 0.001
HDLC (mmol/L) 1.67 ± 0.29 1.39 ± 0.22b 1.17 ± 0.21a/c < 0.001
LDLC (mmol/L) 1.90 ± 0.45 2.31 ± 0.46b 2.79 ± 0.67a/c < 0.001
HbA1c (%) 5.43 ± 0.29 5.43 ± 0.27 5.46 ± 0.29a/c 0.001
FPG (mmol/L) 4.68 ± 0.39 4.70 ± 0.38 4.73 ± 0.37a/c < 0.001
HOMA-IR 1.42 ± 1.28 1.67 ± 1.93b 2.16 ± 2.07a/c < 0.001
Obesity [n (%)] 124 (4.81%) 238 (9.22%)b 551 (21.18%)a/c < 0.001
  1. Data are expressed as the mean ± SD or percentage
  2. BMI Body mass index, ALT Alanine aminotransferase, AST Aminotransferase, ALP Alkaline phosphatase, GGT Gamma-glutamyl transferase, TB Total bilirubin, Cr Creatinine, UA Uric acid, ALB Albumin, TC Total cholesterol, TG Triglycerides, HDLC High-density lipoprotein cholesterol, LDLC Low-density lipoprotein cholesterol, HbA1c Glycated hemoglobin A1c, FPG Fasting plasma glucose, HOMA-IR Homeostasis Model Assessment of Insulin Resistance
  3. aP < 0.05, tertile 3 compared with tertile 1
  4. bP < 0.05, tertile 2 compared with tertile 1
  5. cP < 0.05, tertile 3 compared with tertile 2
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