Fig. 1

Nonproliferative liver lesions. Histopathological features of hematoxylin–eosin and Sirius Red staining and F4/80- and α-SMA-immunohistochemistry (a). Graded from normal (1) to severe (4) (b). The following values are presented as the mean + SD. Sirius Red staining: control chow, 1.00 ± 1.29; CDAA-HF-T(+), 10.82 ± 2.21; CDAA-HF-T(−) 13.29 ± 3.94. F4/80: control chow, 1.00 ± 0.00; CDAA-HF-T(+), 2.20 ± 0.45; CDAA-HF-T(−), 2.75 ± 0.96. α-SMA: control chow, 1.00 ± 0.00; CDAA-HF-T(+), 2.60 ± 0.89; CDAA-HF-T(−), 3.25 ± 0.96. *Significantly different from the control value