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Table 3 Organ weights and plasma and hepatic chemistries at the end of week 13

From: A trans fatty acid substitute enhanced development of liver proliferative lesions induced in mice by feeding a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet

  Control chow CDAA-HF-T(+) CDAA-HF-T(−)
Body weight 26.32 ± 1.71 23.72 ± 1.46a 22.94 ± 0.99a
Liver (g) 1.36 ± 0.06 1.75 ± 0.30a 1.76 ± 0.25a
Liver/BW (%) 4.85 ± 0.14 7.38 ± 0.83a 7.47 ± 0.86a
Kidney (g) 0.36 ± 0.04 0.31 ± 0.06 0.27 ± 0.04a
Heart (g) 0.17 ± 0.05 0.15 ± 0.06 0.12 ± 0.02
eWAT (g) 0.43 ± 0.11 0.60 ± 0.07a 0.51 ± 0.03
eWAT/BW (%) 1.58 ± 0.40 2.53 ± 0.23a 2.19 ± 0.19
TG (mg/dL) 169.13 ± 43.18 106.03 ± 10.51a 110.34 ± 10.45a
TC (mg/dL) 138.71 ± 22.95 101.46 ± 37.72 91.21 ± 8.75
ALT (IU/L) 23.63 ± 0.81 74.26 ± 12.31a 83.58 ± 18.62a
AST (IU/L) 127.36 ± 96.80 323.53 ± 187.72 259.67 ± 18.57a
Liver TG (mg/g) 6.17 ± 3.33 57.91 ± 25.26a 58.93 ± 12.78a
Liver TC (mg/g) 2.42 ± 0.49 3.53 ± 0.45a 3.21 ± 0.26a
  1. Values are presented as the mean ± SD (n = 4–5).
  2. eWAT Epididymal white adipose tissue, TC Total cholesterol, TG Triglyceride.
  3. aSignificantly different from the control value
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Lipids in Health and Disease

ISSN: 1476-511X

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