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Table 3 Organ weights and plasma and hepatic chemistries at the end of week 13

From: A trans fatty acid substitute enhanced development of liver proliferative lesions induced in mice by feeding a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet

 

Control chow

CDAA-HF-T(+)

CDAA-HF-T(−)

Body weight

26.32 ± 1.71

23.72 ± 1.46a

22.94 ± 0.99a

Liver (g)

1.36 ± 0.06

1.75 ± 0.30a

1.76 ± 0.25a

Liver/BW (%)

4.85 ± 0.14

7.38 ± 0.83a

7.47 ± 0.86a

Kidney (g)

0.36 ± 0.04

0.31 ± 0.06

0.27 ± 0.04a

Heart (g)

0.17 ± 0.05

0.15 ± 0.06

0.12 ± 0.02

eWAT (g)

0.43 ± 0.11

0.60 ± 0.07a

0.51 ± 0.03

eWAT/BW (%)

1.58 ± 0.40

2.53 ± 0.23a

2.19 ± 0.19

TG (mg/dL)

169.13 ± 43.18

106.03 ± 10.51a

110.34 ± 10.45a

TC (mg/dL)

138.71 ± 22.95

101.46 ± 37.72

91.21 ± 8.75

ALT (IU/L)

23.63 ± 0.81

74.26 ± 12.31a

83.58 ± 18.62a

AST (IU/L)

127.36 ± 96.80

323.53 ± 187.72

259.67 ± 18.57a

Liver TG (mg/g)

6.17 ± 3.33

57.91 ± 25.26a

58.93 ± 12.78a

Liver TC (mg/g)

2.42 ± 0.49

3.53 ± 0.45a

3.21 ± 0.26a

  1. Values are presented as the mean ± SD (n = 4–5).
  2. eWAT Epididymal white adipose tissue, TC Total cholesterol, TG Triglyceride.
  3. aSignificantly different from the control value