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Table 1 Sample sets used to build PLS models and the model performance in these sample sets

From: The extended lipid panel assay: a clinically-deployed high-throughput nuclear magnetic resonance method for the simultaneous measurement of lipids and Apolipoprotein B

 

Sample Set Characteristics

Model Performance

PLS Model

N

Mean

(mg/dL)

SD

(mg/dL)

Range

(mg/dL)

Latent

Variables

R

RMSECV

(mg/dL)

CVCV

%

TC

3746

181

42

64–476

25

0.987

6.67

3.68

TG

3734

127

68

24–886

27

0.996

5.74

4.51

HDL-C (1)

3453

54

16

14–167

31

0.988

2.50

4.60

HDL-C (2)

1354

38

13

3–104

29

0.976

2.28

6.01

ApoB

969

94

27

35–305

23

0.978

5.53

5.91

  1. TC Total cholesterol; TG Triglycerides; HDL-C HDL cholesterol; ApoB Apolipoprotein B; HDL-C (1), HDL-C model used for samples with TG < 250 mg/dL; HDL-C (2), HDL-C model used for samples with TG ≥250 mg/dL; R, correlation coefficient; RMSECV Root mean square error of cross validation; CVCV Coefficient of variation of cross validation = RMSECV/Mean.