TY - JOUR AU - Berlanga, A. AU - Guiu-Jurado, E. AU - Porras, J. A. AU - Auguet, T. PY - 2014 DA - 2014// TI - Molecular pathways in non-alcoholic fatty liver disease JO - Clin Exp Gastroenterol VL - 7 ID - Berlanga2014 ER - TY - JOUR AU - Buechler, C. AU - Wanninger, J. AU - Neumeier, M. PY - 2011 DA - 2011// TI - Adiponectin, a key adipokine in obesity related liver diseases JO - World J Gastroenterol VL - 17 ID - Buechler2011 ER - TY - JOUR AU - Schaffler, A. AU - Scholmerich, J. AU - Buchler, C. PY - 2005 DA - 2005// TI - Mechanisms of disease: adipocytokines and visceral adipose tissue--emerging role in nonalcoholic fatty liver disease JO - Nat Clin Pract Gastroenterol Hepatol VL - 2 UR - https://doi.org/10.1038/ncpgasthep0186 DO - 10.1038/ncpgasthep0186 ID - Schaffler2005 ER - TY - JOUR AU - Schattenberg, J. M. AU - Galle, P. R. PY - 2010 DA - 2010// TI - Animal models of non-alcoholic steatohepatitis: of mice and man JO - Dig Dis VL - 28 UR - https://doi.org/10.1159/000282097 DO - 10.1159/000282097 ID - Schattenberg2010 ER - TY - JOUR AU - Rein-Fischboeck, L. AU - Haberl, E. M. AU - Pohl, R. AU - Feder, S. AU - Liebisch, G. AU - Krautbauer, S. AU - Buechler, C. PY - 2019 DA - 2019// TI - Variations in hepatic lipid species of age-matched male mice fed a methionine-choline-deficient diet and housed in different animal facilities JO - Lipids Health Dis VL - 18 UR - https://doi.org/10.1186/s12944-019-1114-4 DO - 10.1186/s12944-019-1114-4 ID - Rein-Fischboeck2019 ER - TY - JOUR AU - Rein-Fischboeck, L. AU - Haberl, E. M. AU - Pohl, R. AU - Schmid, V. AU - Feder, S. AU - Krautbauer, S. AU - Liebisch, G. AU - Buechler, C. PY - 1863 DA - 1863// TI - Alpha-syntrophin null mice are protected from non-alcoholic steatohepatitis in the methionine-choline-deficient diet model but not the atherogenic diet model JO - Biochim Biophys Acta VL - 2018 ID - Rein-Fischboeck1863 ER - TY - JOUR AU - Bakiri, L. AU - Wagner, E. F. PY - 2013 DA - 2013// TI - Mouse models for liver cancer JO - Mol Oncol VL - 7 UR - https://doi.org/10.1016/j.molonc.2013.01.005 DO - 10.1016/j.molonc.2013.01.005 ID - Bakiri2013 ER - TY - JOUR AU - Matsumoto, M. AU - Hada, N. AU - Sakamaki, Y. AU - Uno, A. AU - Shiga, T. AU - Tanaka, C. AU - Ito, T. AU - Katsume, A. AU - Sudoh, M. PY - 2013 DA - 2013// TI - An improved mouse model that rapidly develops fibrosis in non-alcoholic steatohepatitis JO - Int J Exp Pathol VL - 94 UR - https://doi.org/10.1111/iep.12008 DO - 10.1111/iep.12008 ID - Matsumoto2013 ER - TY - JOUR AU - Haberl, E. M. AU - Pohl, R. AU - Rein-Fischboeck, L. AU - Feder, S. AU - Sinal, C. J. AU - Buechler, C. PY - 2018 DA - 2018// TI - Chemerin in a mouse model of non-alcoholic Steatohepatitis and Hepatocarcinogenesis JO - Anticancer Res VL - 38 ID - Haberl2018 ER - TY - JOUR AU - Neuschwander-Tetri, B. A. PY - 2010 DA - 2010// TI - Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: the central role of nontriglyceride fatty acid metabolites JO - Hepatology. VL - 52 UR - https://doi.org/10.1002/hep.23719 DO - 10.1002/hep.23719 ID - Neuschwander-Tetri2010 ER - TY - JOUR AU - Buechler, C. AU - Aslanidis, C. PY - 2020 DA - 2020// TI - Role of lipids in pathophysiology, diagnosis and therapy of hepatocellular carcinoma JO - Biochim Biophys Acta Mol Cell Biol Lipids VL - 1865 UR - https://doi.org/10.1016/j.bbalip.2020.158658 DO - 10.1016/j.bbalip.2020.158658 ID - Buechler2020 ER - TY - JOUR AU - Montgomery, M. K. AU - Brown, S. H. AU - Lim, X. Y. AU - Fiveash, C. E. AU - Osborne, B. AU - Bentley, N. L. AU - Braude, J. P. AU - Mitchell, T. W. AU - Coster, A. C. AU - Don, A. S. PY - 2016 DA - 2016// TI - Regulation of glucose homeostasis and insulin action by ceramide acyl-chain length: a beneficial role for very long-chain sphingolipid species JO - Biochim Biophys Acta VL - 1861 UR - https://doi.org/10.1016/j.bbalip.2016.08.016 DO - 10.1016/j.bbalip.2016.08.016 ID - Montgomery2016 ER - TY - JOUR AU - Ioannou, G. N. PY - 2016 DA - 2016// TI - The role of cholesterol in the pathogenesis of NASH JO - Trends Endocrinol Metab VL - 27 UR - https://doi.org/10.1016/j.tem.2015.11.008 DO - 10.1016/j.tem.2015.11.008 ID - Ioannou2016 ER - TY - JOUR AU - Cano, A. AU - Alonso, C. PY - 2014 DA - 2014// TI - Deciphering non-alcoholic fatty liver disease through metabolomics JO - Biochem Soc Trans VL - 42 UR - https://doi.org/10.1042/BST20140138 DO - 10.1042/BST20140138 ID - Cano2014 ER - TY - JOUR AU - Giudetti, A. M. AU - Domenico, S. AU - Ragusa, A. AU - Lunetti, P. AU - Gaballo, A. AU - Franck, J. AU - Simeone, P. AU - Nicolardi, G. AU - Nuccio, F. AU - Santino, A. PY - 2019 DA - 2019// TI - A specific lipid metabolic profile is associated with the epithelial mesenchymal transition program JO - Biochim Biophys Acta Mol Cell Biol Lipids VL - 1864 UR - https://doi.org/10.1016/j.bbalip.2018.12.011 DO - 10.1016/j.bbalip.2018.12.011 ID - Giudetti2019 ER - TY - JOUR AU - Garattini, S. AU - Grignaschi, G. PY - 2017 DA - 2017// TI - Animal testing is still the best way to find new treatments for patients JO - Eur J Intern Med VL - 39 UR - https://doi.org/10.1016/j.ejim.2016.11.013 DO - 10.1016/j.ejim.2016.11.013 ID - Garattini2017 ER - TY - JOUR AU - Liu, M. AU - Yan, Q. AU - Sun, Y. AU - Nam, Y. AU - Hu, L. AU - Loong, J. H. AU - Ouyang, Q. AU - Zhang, Y. AU - Li, H. L. AU - Kong, F. E. PY - 2020 DA - 2020// TI - A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties and therapeutic targets JO - Proc Natl Acad Sci U S A VL - 117 UR - https://doi.org/10.1073/pnas.1912146117 DO - 10.1073/pnas.1912146117 ID - Liu2020 ER - TY - JOUR AU - Liebisch, G. AU - Binder, M. AU - Schifferer, R. AU - Langmann, T. AU - Schulz, B. AU - Schmitz, G. PY - 1761 DA - 1761// TI - High throughput quantification of cholesterol and cholesteryl ester by electrospray ionization tandem mass spectrometry (ESI-MS/MS) JO - Biochim Biophys Acta VL - 2006 ID - Liebisch1761 ER - TY - JOUR AU - Liebisch, G. AU - Lieser, B. AU - Rathenberg, J. AU - Drobnik, W. AU - Schmitz, G. PY - 2004 DA - 2004// TI - High-throughput quantification of phosphatidylcholine and sphingomyelin by electrospray ionization tandem mass spectrometry coupled with isotope correction algorithm JO - Biochim Biophys Acta VL - 1686 UR - https://doi.org/10.1016/j.bbalip.2004.09.003 DO - 10.1016/j.bbalip.2004.09.003 ID - Liebisch2004 ER - TY - JOUR AU - Liebisch, G. AU - Drobnik, W. AU - Lieser, B. AU - Schmitz, G. PY - 2002 DA - 2002// TI - High-throughput quantification of lysophosphatidylcholine by electrospray ionization tandem mass spectrometry JO - Clin Chem VL - 48 UR - https://doi.org/10.1093/clinchem/48.12.2217 DO - 10.1093/clinchem/48.12.2217 ID - Liebisch2002 ER - TY - JOUR AU - Matyash, V. AU - Liebisch, G. AU - Kurzchalia, T. V. AU - Shevchenko, A. AU - Schwudke, D. PY - 2008 DA - 2008// TI - Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics JO - J Lipid Res VL - 49 UR - https://doi.org/10.1194/jlr.D700041-JLR200 DO - 10.1194/jlr.D700041-JLR200 ID - Matyash2008 ER - TY - JOUR AU - Zemski Berry, K. A. AU - Murphy, R. C. PY - 2004 DA - 2004// TI - Electrospray ionization tandem mass spectrometry of glycerophosphoethanolamine plasmalogen phospholipids JO - J Am Soc Mass Spectrom VL - 15 UR - https://doi.org/10.1016/j.jasms.2004.07.009 DO - 10.1016/j.jasms.2004.07.009 ID - Zemski Berry2004 ER - TY - JOUR AU - Liebisch, G. AU - Drobnik, W. AU - Reil, M. AU - Trumbach, B. AU - Arnecke, R. AU - Olgemoller, B. AU - Roscher, A. AU - Schmitz, G. PY - 1999 DA - 1999// TI - Quantitative measurement of different ceramide species from crude cellular extracts by electrospray ionization tandem mass spectrometry (ESI-MS/MS) JO - J Lipid Res VL - 40 ID - Liebisch1999 ER - TY - JOUR AU - Horing, M. AU - Ejsing, C. S. AU - Hermansson, M. AU - Liebisch, G. PY - 2019 DA - 2019// TI - Quantification of cholesterol and Cholesteryl Ester by direct flow injection high-resolution Fourier transform mass spectrometry utilizing species-specific response factors JO - Anal Chem VL - 91 UR - https://doi.org/10.1021/acs.analchem.8b05013 DO - 10.1021/acs.analchem.8b05013 ID - Horing2019 ER - TY - JOUR AU - Husen, P. AU - Tarasov, K. AU - Katafiasz, M. AU - Sokol, E. AU - Vogt, J. AU - Baumgart, J. AU - Nitsch, R. AU - Ekroos, K. AU - Ejsing, C. S. PY - 2013 DA - 2013// TI - Analysis of lipid experiments (ALEX): a software framework for analysis of high-resolution shotgun lipidomics data JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0079736 DO - 10.1371/journal.pone.0079736 ID - Husen2013 ER - TY - JOUR AU - Horing, M. AU - Ekroos, K. AU - Baker, P. R. S. AU - Connell, L. AU - Stadler, S. C. AU - Burkhardt, R. AU - Liebisch, G. PY - 2020 DA - 2020// TI - Correction of isobaric overlap resulting from sodiated ions in lipidomics JO - Anal Chem VL - 92 UR - https://doi.org/10.1021/acs.analchem.0c02408 DO - 10.1021/acs.analchem.0c02408 ID - Horing2020 ER - TY - JOUR AU - Liebisch, G. AU - Vizcaino, J. A. AU - Kofeler, H. AU - Trotzmuller, M. AU - Griffiths, W. J. AU - Schmitz, G. AU - Spener, F. AU - Wakelam, M. J. PY - 2013 DA - 2013// TI - Shorthand notation for lipid structures derived from mass spectrometry JO - J Lipid Res VL - 54 UR - https://doi.org/10.1194/jlr.M033506 DO - 10.1194/jlr.M033506 ID - Liebisch2013 ER - TY - JOUR AU - Bligh, E. G. AU - Dyer, W. J. PY - 1959 DA - 1959// TI - A rapid method of total lipid extraction and purification JO - Can J Biochem Physiol VL - 37 UR - https://doi.org/10.1139/o59-099 DO - 10.1139/o59-099 ID - Bligh1959 ER - TY - JOUR AU - Schneider, C. A. AU - Rasband, W. S. AU - Eliceiri, K. W. PY - 2012 DA - 2012// TI - NIH image to ImageJ: 25 years of image analysis JO - Nat Methods VL - 9 UR - https://doi.org/10.1038/nmeth.2089 DO - 10.1038/nmeth.2089 ID - Schneider2012 ER - TY - JOUR AU - Beneduce, L. AU - Castaldi, F. AU - Marino, M. AU - Tono, N. AU - Gatta, A. AU - Pontisso, P. AU - Fassina, G. PY - 2004 DA - 2004// TI - Improvement of liver cancer detection with simultaneous assessment of circulating levels of free alpha-fetoprotein (AFP) and AFP-IgM complexes JO - Int J Biol Markers VL - 19 UR - https://doi.org/10.1177/172460080401900211 DO - 10.1177/172460080401900211 ID - Beneduce2004 ER - TY - JOUR AU - Horton, J. D. PY - 2002 DA - 2002// TI - Sterol regulatory element-binding proteins: transcriptional activators of lipid synthesis JO - Biochem Soc Trans VL - 30 UR - https://doi.org/10.1042/bst0301091 DO - 10.1042/bst0301091 ID - Horton2002 ER - TY - JOUR AU - Millar, J. S. AU - Stone, S. J. AU - Tietge, U. J. AU - Tow, B. AU - Billheimer, J. T. AU - Wong, J. S. AU - Hamilton, R. L. AU - Farese, R. V. AU - Rader, D. J. PY - 2006 DA - 2006// TI - Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production JO - J Lipid Res VL - 47 UR - https://doi.org/10.1194/jlr.M600213-JLR200 DO - 10.1194/jlr.M600213-JLR200 ID - Millar2006 ER - TY - JOUR AU - Luukkonen, P. K. AU - Zhou, Y. AU - Sadevirta, S. AU - Leivonen, M. AU - Arola, J. AU - Oresic, M. AU - Hyotylainen, T. AU - Yki-Jarvinen, H. PY - 2016 DA - 2016// TI - Hepatic ceramides dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease JO - J Hepatol VL - 64 UR - https://doi.org/10.1016/j.jhep.2016.01.002 DO - 10.1016/j.jhep.2016.01.002 ID - Luukkonen2016 ER - TY - JOUR AU - Gault, C. R. AU - Obeid, L. M. AU - Hannun, Y. A. PY - 2010 DA - 2010// TI - An overview of sphingolipid metabolism: from synthesis to breakdown JO - Adv Exp Med Biol VL - 688 UR - https://doi.org/10.1007/978-1-4419-6741-1_1 DO - 10.1007/978-1-4419-6741-1_1 ID - Gault2010 ER - TY - JOUR AU - Apostolopoulou, M. AU - Gordillo, R. AU - Koliaki, C. AU - Gancheva, S. AU - Jelenik, T. AU - Filippo, E. AU - Herder, C. AU - Markgraf, D. AU - Jankowiak, F. AU - Esposito, I. PY - 2018 DA - 2018// TI - Specific hepatic Sphingolipids relate to insulin resistance, oxidative stress, and inflammation in nonalcoholic Steatohepatitis JO - Diabetes Care VL - 41 UR - https://doi.org/10.2337/dc17-1318 DO - 10.2337/dc17-1318 ID - Apostolopoulou2018 ER - TY - JOUR AU - Chiappini, F. AU - Coilly, A. AU - Kadar, H. AU - Gual, P. AU - Tran, A. AU - Desterke, C. AU - Samuel, D. AU - Duclos-Vallee, J. C. AU - Touboul, D. AU - Bertrand-Michel, J. PY - 2017 DA - 2017// TI - Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/srep46658 DO - 10.1038/srep46658 ID - Chiappini2017 ER - TY - JOUR AU - Puri, P. AU - Baillie, R. A. AU - Wiest, M. M. AU - Mirshahi, F. AU - Choudhury, J. AU - Cheung, O. AU - Sargeant, C. AU - Contos, M. J. AU - Sanyal, A. J. PY - 2007 DA - 2007// TI - A lipidomic analysis of nonalcoholic fatty liver disease JO - Hepatology. VL - 46 UR - https://doi.org/10.1002/hep.21763 DO - 10.1002/hep.21763 ID - Puri2007 ER - TY - JOUR AU - Musso, G. AU - Cassader, M. AU - Paschetta, E. AU - Gambino, R. PY - 2018 DA - 2018// TI - Bioactive lipid species and metabolic pathways in progression and resolution of nonalcoholic Steatohepatitis JO - Gastroenterology VL - 155 UR - https://doi.org/10.1053/j.gastro.2018.06.031 DO - 10.1053/j.gastro.2018.06.031 ID - Musso2018 ER - TY - JOUR AU - Krautbauer, S. AU - Meier, E. M. AU - Rein-Fischboeck, L. AU - Pohl, R. AU - Weiss, T. S. AU - Sigruener, A. AU - Aslanidis, C. AU - Liebisch, G. AU - Buechler, C. PY - 2016 DA - 2016// TI - Ceramide and polyunsaturated phospholipids are strongly reduced in human hepatocellular carcinoma JO - Biochim Biophys Acta VL - 1861 UR - https://doi.org/10.1016/j.bbalip.2016.08.014 DO - 10.1016/j.bbalip.2016.08.014 ID - Krautbauer2016 ER - TY - JOUR AU - Gorden, D. L. AU - Ivanova, P. T. AU - Myers, D. S. AU - McIntyre, J. O. AU - VanSaun, M. N. AU - Wright, J. K. AU - Matrisian, L. M. AU - Brown, H. A. PY - 2011 DA - 2011// TI - Increased diacylglycerols characterize hepatic lipid changes in progression of human nonalcoholic fatty liver disease; comparison to a murine model JO - PLoS One VL - 6 UR - https://doi.org/10.1371/journal.pone.0022775 DO - 10.1371/journal.pone.0022775 ID - Gorden2011 ER - TY - JOUR AU - Caballero, F. AU - Fernandez, A. AU - Matias, N. AU - Martinez, L. AU - Fucho, R. AU - Elena, M. AU - Caballeria, J. AU - Morales, A. AU - Fernandez-Checa, J. C. AU - Garcia-Ruiz, C. PY - 2010 DA - 2010// TI - Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione JO - J Biol Chem VL - 285 UR - https://doi.org/10.1074/jbc.M109.099333 DO - 10.1074/jbc.M109.099333 ID - Caballero2010 ER - TY - JOUR AU - Ayala, A. AU - Munoz, M. F. AU - Arguelles, S. PY - 2014 DA - 2014// TI - Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal JO - Oxidative Med Cell Longev VL - 2014 UR - https://doi.org/10.1155/2014/360438 DO - 10.1155/2014/360438 ID - Ayala2014 ER - TY - JOUR AU - Kasumov, T. AU - Li, L. AU - Li, M. AU - Gulshan, K. AU - Kirwan, J. P. AU - Liu, X. AU - Previs, S. AU - Willard, B. AU - Smith, J. D. AU - McCullough, A. PY - 2015 DA - 2015// TI - Ceramide as a mediator of non-alcoholic fatty liver disease and associated atherosclerosis JO - PLoS One VL - 10 UR - https://doi.org/10.1371/journal.pone.0126910 DO - 10.1371/journal.pone.0126910 ID - Kasumov2015 ER - TY - JOUR AU - Eisinger, K. AU - Krautbauer, S. AU - Hebel, T. AU - Schmitz, G. AU - Aslanidis, C. AU - Liebisch, G. AU - Buechler, C. PY - 2014 DA - 2014// TI - Lipidomic analysis of the liver from high-fat diet induced obese mice identifies changes in multiple lipid classes JO - Exp Mol Pathol VL - 97 UR - https://doi.org/10.1016/j.yexmp.2014.05.002 DO - 10.1016/j.yexmp.2014.05.002 ID - Eisinger2014 ER - TY - JOUR AU - Laggai, S. AU - Simon, Y. AU - Ranssweiler, T. AU - Kiemer, A. K. AU - Kessler, S. M. PY - 2013 DA - 2013// TI - Rapid chromatographic method to decipher distinct alterations in lipid classes in NAFLD/NASH JO - World J Hepatol VL - 5 UR - https://doi.org/10.4254/wjh.v5.i10.558 DO - 10.4254/wjh.v5.i10.558 ID - Laggai2013 ER - TY - JOUR AU - Mas, E. AU - Danjoux, M. AU - Garcia, V. AU - Carpentier, S. AU - Segui, B. AU - Levade, T. PY - 2009 DA - 2009// TI - IL-6 deficiency attenuates murine diet-induced non-alcoholic steatohepatitis JO - PLoS One VL - 4 UR - https://doi.org/10.1371/journal.pone.0007929 DO - 10.1371/journal.pone.0007929 ID - Mas2009 ER - TY - JOUR AU - Najt, C. P. AU - Senthivinayagam, S. AU - Aljazi, M. B. AU - Fader, K. A. AU - Olenic, S. D. AU - Brock, J. R. AU - Lydic, T. A. AU - Jones, A. D. AU - Atshaves, B. P. PY - 2016 DA - 2016// TI - Liver-specific loss of Perilipin 2 alleviates diet-induced hepatic steatosis, inflammation, and fibrosis JO - Am J Physiol Gastrointest Liver Physiol VL - 310 UR - https://doi.org/10.1152/ajpgi.00436.2015 DO - 10.1152/ajpgi.00436.2015 ID - Najt2016 ER - TY - JOUR AU - Niebergall, L. J. AU - Jacobs, R. L. AU - Chaba, T. AU - Vance, D. E. PY - 2011 DA - 2011// TI - Phosphatidylcholine protects against steatosis in mice but not non-alcoholic steatohepatitis JO - Biochim Biophys Acta VL - 1811 UR - https://doi.org/10.1016/j.bbalip.2011.06.021 DO - 10.1016/j.bbalip.2011.06.021 ID - Niebergall2011 ER - TY - JOUR AU - Cui, Z. AU - Houweling, M. AU - Vance, D. E. PY - 1995 DA - 1995// TI - Expression of phosphatidylethanolamine N-methyltransferase-2 in McArdle-RH7777 hepatoma cells inhibits the CDP-choline pathway for phosphatidylcholine biosynthesis via decreased gene expression of CTP:phosphocholine cytidylyltransferase JO - Biochem J VL - 312 UR - https://doi.org/10.1042/bj3120939 DO - 10.1042/bj3120939 ID - Cui1995 ER - TY - JOUR AU - Kulinski, A. AU - Vance, D. E. AU - Vance, J. E. PY - 2004 DA - 2004// TI - A choline-deficient diet in mice inhibits neither the CDP-choline pathway for phosphatidylcholine synthesis in hepatocytes nor apolipoprotein B secretion JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M312676200 DO - 10.1074/jbc.M312676200 ID - Kulinski2004 ER - TY - JOUR AU - Li, Z. AU - Agellon, L. B. AU - Allen, T. M. AU - Umeda, M. AU - Jewell, L. AU - Mason, A. AU - Vance, D. E. PY - 2006 DA - 2006// TI - The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis JO - Cell Metab VL - 3 UR - https://doi.org/10.1016/j.cmet.2006.03.007 DO - 10.1016/j.cmet.2006.03.007 ID - Li2006 ER - TY - JOUR AU - Arendt, B. M. AU - Ma, D. W. AU - Simons, B. AU - Noureldin, S. A. AU - Therapondos, G. AU - Guindi, M. AU - Sherman, M. AU - Allard, J. P. PY - 2013 DA - 2013// TI - Nonalcoholic fatty liver disease is associated with lower hepatic and erythrocyte ratios of phosphatidylcholine to phosphatidylethanolamine JO - Appl Physiol Nutr Metab VL - 38 UR - https://doi.org/10.1139/apnm-2012-0261 DO - 10.1139/apnm-2012-0261 ID - Arendt2013 ER - TY - JOUR AU - Eisinger, K. AU - Liebisch, G. AU - Schmitz, G. AU - Aslanidis, C. AU - Krautbauer, S. AU - Buechler, C. PY - 2014 DA - 2014// TI - Lipidomic analysis of serum from high fat diet induced obese mice JO - Int J Mol Sci VL - 15 UR - https://doi.org/10.3390/ijms15022991 DO - 10.3390/ijms15022991 ID - Eisinger2014 ER - TY - JOUR AU - Patterson, A. D. AU - Maurhofer, O. AU - Beyoglu, D. AU - Lanz, C. AU - Krausz, K. W. AU - Pabst, T. AU - Gonzalez, F. J. AU - Dufour, J. F. AU - Idle, J. R. PY - 2011 DA - 2011// TI - Aberrant lipid metabolism in hepatocellular carcinoma revealed by plasma metabolomics and lipid profiling JO - Cancer Res VL - 71 UR - https://doi.org/10.1158/0008-5472.CAN-11-0885 DO - 10.1158/0008-5472.CAN-11-0885 ID - Patterson2011 ER - TY - JOUR AU - Tanaka, N. AU - Matsubara, T. AU - Krausz, K. W. AU - Patterson, A. D. AU - Gonzalez, F. J. PY - 2012 DA - 2012// TI - Disruption of phospholipid and bile acid homeostasis in mice with nonalcoholic steatohepatitis JO - Hepatology. VL - 56 UR - https://doi.org/10.1002/hep.25630 DO - 10.1002/hep.25630 ID - Tanaka2012 ER - TY - JOUR AU - Zhou, L. AU - Ding, L. AU - Yin, P. AU - Lu, X. AU - Wang, X. AU - Niu, J. AU - Gao, P. AU - Xu, G. PY - 2012 DA - 2012// TI - Serum metabolic profiling study of hepatocellular carcinoma infected with hepatitis B or hepatitis C virus by using liquid chromatography-mass spectrometry JO - J Proteome Res VL - 11 UR - https://doi.org/10.1021/pr300683a DO - 10.1021/pr300683a ID - Zhou2012 ER - TY - JOUR AU - Ackerman, D. AU - Tumanov, S. AU - Qiu, B. AU - Michalopoulou, E. AU - Spata, M. AU - Azzam, A. AU - Xie, H. AU - Simon, M. C. AU - Kamphorst, J. J. PY - 2018 DA - 2018// TI - Triglycerides promote lipid homeostasis during hypoxic stress by balancing fatty acid saturation JO - Cell Rep VL - 24 UR - https://doi.org/10.1016/j.celrep.2018.08.015 DO - 10.1016/j.celrep.2018.08.015 ID - Ackerman2018 ER - TY - JOUR AU - Kudo, Y. AU - Tanaka, Y. AU - Tateishi, K. AU - Yamamoto, K. AU - Yamamoto, S. AU - Mohri, D. AU - Isomura, Y. AU - Seto, M. AU - Nakagawa, H. AU - Asaoka, Y. PY - 2011 DA - 2011// TI - Altered composition of fatty acids exacerbates hepatotumorigenesis during activation of the phosphatidylinositol 3-kinase pathway JO - J Hepatol VL - 55 UR - https://doi.org/10.1016/j.jhep.2011.03.025 DO - 10.1016/j.jhep.2011.03.025 ID - Kudo2011 ER - TY - JOUR AU - Duan, X. Y. AU - Pan, Q. AU - Yan, S. Y. AU - Ding, W. J. AU - Fan, J. G. AU - Qiao, L. PY - 2014 DA - 2014// TI - High-saturate-fat diet delays initiation of diethylnitrosamine-induced hepatocellular carcinoma JO - BMC Gastroenterol VL - 14 UR - https://doi.org/10.1186/s12876-014-0195-9 DO - 10.1186/s12876-014-0195-9 ID - Duan2014 ER - TY - JOUR AU - Glauert, H. P. AU - Lay, L. T. AU - Kennan, W. S. AU - Pitot, H. C. PY - 1991 DA - 1991// TI - Effect of dietary fat on the initiation of hepatocarcinogenesis by diethylnitrosamine or 2-acetylaminofluorene in rats JO - Carcinogenesis VL - 12 UR - https://doi.org/10.1093/carcin/12.6.991 DO - 10.1093/carcin/12.6.991 ID - Glauert1991 ER - TY - JOUR AU - Vriens, K. AU - Christen, S. AU - Parik, S. AU - Broekaert, D. AU - Yoshinaga, K. AU - Talebi, A. AU - Dehairs, J. AU - Escalona-Noguero, C. AU - Schmieder, R. AU - Cornfield, T. PY - 2019 DA - 2019// TI - Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity JO - Nature. VL - 566 UR - https://doi.org/10.1038/s41586-019-0904-1 DO - 10.1038/s41586-019-0904-1 ID - Vriens2019 ER - TY - JOUR AU - Newton, A. C. PY - 2018 DA - 2018// TI - Protein kinase C: perfectly balanced JO - Crit Rev Biochem Mol Biol VL - 53 UR - https://doi.org/10.1080/10409238.2018.1442408 DO - 10.1080/10409238.2018.1442408 ID - Newton2018 ER - TY - STD TI - Li Z, Guan M, Lin Y, Cui X, Zhang Y, Zhao Z, Zhu J. Aberrant lipid metabolism in hepatocellular carcinoma revealed by liver Lipidomics. Int J Mol Sci. 2017;18:2550. ID - ref63 ER - TY - STD TI - Berndt N, Eckstein J, Heucke N, Gajowski R, Stockmann M, Meierhofer D, Holzhutter HG. Characterization of lipid and lipid droplet metabolism in human HCC. Cells. 2019;8:512. ID - ref64 ER - TY - JOUR AU - Matteis, S. AU - Ragusa, A. AU - Marisi, G. AU - Domenico, S. AU - Casadei Gardini, A. AU - Bonafe, M. AU - Giudetti, A. M. PY - 2018 DA - 2018// TI - Aberrant metabolism in hepatocellular carcinoma provides diagnostic and therapeutic opportunities JO - Oxidative Med Cell Longev VL - 2018 UR - https://doi.org/10.1155/2018/7512159 DO - 10.1155/2018/7512159 ID - Matteis2018 ER - TY - JOUR AU - Che, L. AU - Pilo, M. G. AU - Cigliano, A. AU - Latte, G. AU - Simile, M. M. AU - Ribback, S. AU - Dombrowski, F. AU - Evert, M. AU - Chen, X. AU - Calvisi, D. F. PY - 2017 DA - 2017// TI - Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma JO - Cell Cycle VL - 16 UR - https://doi.org/10.1080/15384101.2017.1282586 DO - 10.1080/15384101.2017.1282586 ID - Che2017 ER - TY - JOUR AU - Nelson, M. E. AU - Lahiri, S. AU - Chow, J. D. AU - Byrne, F. L. AU - Hargett, S. R. AU - Breen, D. S. AU - Olzomer, E. M. AU - Wu, L. E. AU - Cooney, G. J. AU - Turner, N. PY - 2017 DA - 2017// TI - Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival JO - Nat Commun VL - 8 UR - https://doi.org/10.1038/ncomms14689 DO - 10.1038/ncomms14689 ID - Nelson2017 ER - TY - JOUR AU - Jovel, J. AU - Lin, Z. AU - O'Keefe, S. AU - Willows, S. AU - Wang, W. AU - Zhang, G. AU - Patterson, J. AU - Moctezuma-Velazquez, C. AU - Kelvin, D. J. AU - Ka-Shu Wong, G. AU - Mason, A. L. PY - 2018 DA - 2018// TI - A survey of molecular heterogeneity in hepatocellular carcinoma JO - Hepatol Commun VL - 2 UR - https://doi.org/10.1002/hep4.1197 DO - 10.1002/hep4.1197 ID - Jovel2018 ER -