Association between lipoprotein cholesterol and future cardiovascular disease and mortality in older adults: a Korean nationwide longitudinal study

Table 2 Association between quartiles of low-density lipoprotein cholesterol and cardiovascular disease

	Event	Duration (PYs)	Incidence rate	Crude	Model 1	Model 2	Model 3
				HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)
				β x 10⁴ (P-value**)	β x 10⁴ (P-value**)	β x 10⁴ (P-value**)	β x 10⁴ (P-value**)
Cardiovascular event
Ischemic heart disease	198	204025.6	0.970	0.90 (0.79–1.03)	0.90 (0.79–1.03)	0.95 (0.83–1.09)	0.95 (0.83–1.09)
				-4.170 (0.041)	-2.874 (0.164)	-2.874 (0.165)	-1.159 (0.633)
Ischemic brain disease	125	204025.6	0.613	0.80 (0.68–0.94)	0.83 (0.70–0.98)	0.83 (0.70–0.98)	0.84 (0.70–1.00)
				-4.019 (0.013)	-3.450 (0.036)	-3.454 (0.036)	-3.389 (0.078)
Total	323	204025.6	1.583	0.83 (0.75–0.92)	0.87 (0.79–0.97)	0.90 (0.81–1.01)	0.90 (0.81–1.01)
				-8.189 (0.002)	-6.324 (0.017)	-6.328 (0.016)	-4.548 (0.142)
Cardiovascular death
Ischemic heart disease	45	204058.7	0.221	0.88 (0.68–1.16)	0.99 (0.75–1.29)	0.99 (0.75–1.29)	1.13 (0.83–1.54)
				-0.708 (0.467)	-0.017 (0.986)	-0.022 (0.982)	0.961 (0.381)
Ischemic brain disease	69	204058.7	0.338	0.90 (0.73–1.12)	0.93 (0.75–1.16)	0.93 (0.75–1.16)	0.95 (0.74–1.22)
				0.572 (0.543)	0.934 (0.327)	0.932 (0.329)	1.709 (0.103)
Total	114	204058.7	0.559	0.89 (0.76–1.06)	0.95 (0.80–1.13)	0.95 (0.80–1.13)	1.01 (0.84–1.23)
				-1.617 (0.297)	-0.655 (0.677)	-0.663 (0.673)	-0.701 (0.687)

ISSN: 1476-511X