| |
Event
|
Duration (PYs)
|
Incidence rate
|
Crude
|
Model 1
|
Model 2
|
Model 3
|
|---|
|
HR (95% CI)
|
HR (95% CI)
|
HR (95% CI)
|
HR (95% CI)
|
|---|
|
β x 104 (P-value**)
|
β x 104 (P-value**)
|
β x 104 (P-value**)
|
β x 104 (P-value**)
|
|---|
|
Cardiovascular event
|
|
Ischemic heart disease
|
198
|
204025.6
|
0.970
|
0.90 (0.79–1.03)
|
0.90 (0.79–1.03)
|
0.95 (0.83–1.09)
|
0.95 (0.83–1.09)
|
| | | | |
-4.170 (0.041)
|
-2.874 (0.164)
|
-2.874 (0.165)
|
-1.159 (0.633)
|
|
Ischemic brain disease
|
125
|
204025.6
|
0.613
|
0.80 (0.68–0.94)
|
0.83 (0.70–0.98)
|
0.83 (0.70–0.98)
|
0.84 (0.70–1.00)
|
| | | | |
-4.019 (0.013)
|
-3.450 (0.036)
|
-3.454 (0.036)
|
-3.389 (0.078)
|
|
Total
|
323
|
204025.6
|
1.583
|
0.83 (0.75–0.92)
|
0.87 (0.79–0.97)
|
0.90 (0.81–1.01)
|
0.90 (0.81–1.01)
|
| | | | |
-8.189 (0.002)
|
-6.324 (0.017)
|
-6.328 (0.016)
|
-4.548 (0.142)
|
|
Cardiovascular death
|
|
Ischemic heart disease
|
45
|
204058.7
|
0.221
|
0.88 (0.68–1.16)
|
0.99 (0.75–1.29)
|
0.99 (0.75–1.29)
|
1.13 (0.83–1.54)
|
| | | | |
-0.708 (0.467)
|
-0.017 (0.986)
|
-0.022 (0.982)
|
0.961 (0.381)
|
|
Ischemic brain disease
|
69
|
204058.7
|
0.338
|
0.90 (0.73–1.12)
|
0.93 (0.75–1.16)
|
0.93 (0.75–1.16)
|
0.95 (0.74–1.22)
|
| | | | |
0.572 (0.543)
|
0.934 (0.327)
|
0.932 (0.329)
|
1.709 (0.103)
|
|
Total
|
114
|
204058.7
|
0.559
|
0.89 (0.76–1.06)
|
0.95 (0.80–1.13)
|
0.95 (0.80–1.13)
|
1.01 (0.84–1.23)
|
| | | | |
-1.617 (0.297)
|
-0.655 (0.677)
|
-0.663 (0.673)
|
-0.701 (0.687)
|
- Model 1: age, sex
- Model 2: Model 1 + cigarette smoking
- Model 3: Model 2 + hypertension, diabetes mellitus, body mass index
- *Abbreviation: PY Person-year, HR Hazard ratio, CI Confidence interval
- Incidence rate is for the total participants.
- HR is for the 4th quartile compared to the 1st quartile.
- ** P-value is for β coefficient of multiple linear regression analysis.
