Skip to main content

Table 3 Association between quartiles of high-density lipoprotein cholesterol and cardiovascular disease

From: Association between lipoprotein cholesterol and future cardiovascular disease and mortality in older adults: a Korean nationwide longitudinal study

  Event Duration (PYs) Incidence rate Crude Model 1 Model 2 Model 3
HR (95% CI) HR (95% CI) HR (95% CI) HR (95% CI)
β x 104 (P-value**) β x 104 (P-value**) β x 104 (P-value**) β x 104 (P-value**)
Cardiovascular event
 Ischemic heart disease 198 204025.6 0.970 0.88 (0.77–1.00) 0.90 (0.80–1.03) 0.90 (0.80–1.03) 0.95 (0.83–1.09)
     -3.789 (0.057) -2.804 (0.163) -2.832 (0.159) -1.293 (0.585)
 Ischemic brain disease 125 204025.6 0.613 0.95 (0.82–1.12) 0.98 (0.83–1.14) 0.98 (0.84–1.15) 0.94 (0.79–1.12)
     -0.784 (0.621) -0.292 (0.855) -0.262 (0.870) -0.960 (0.610)
 Total 323 204025.6 1.583 0.91 (0.82–1.00) 0.93 (0.85–1.03) 0.93 (0.85–1.03) 0.95 (0.85–1.05)
     -4.573 (0.041) -3.096 (0.164) -3.094 (0.165) -2.252 (0.633)
Cardiovascular death
 Ischemic heart disease 45 204058.7 0.221 0.79 (0.61–1.04) 0.84 (0.65–1.10) 0.85 (0.65–1.11) 0.82 (0.60–1.11)
     -1.543 (0.105) -1.041 (0.278) -0.993 (0.301) -1.237 (0.248)
 Ischemic brain disease 69 204058.7 0.338 1.04 (0.84–1.28) 1.06 (0.86–1.31) 1.06 (0.86–1.31) 1.10 (0.87–1.40)
     -1.121 (0.223) -0.881 (0.342) -0.846 (0.361) -0.551 (0.591)
 Total 114 204058.7 0.559 0.93 (0.79–1.10) 0.98 (0.83–1.15) 0.98 (0.83–1.15) 0.98 (0.81–1.19)
     -1.043 (0.491) -0.312 (0.838) -0.222 (0.884) -0.113 (0.947)
  1. Model 1: age, sex
  2. Model 2: Model 1 + cigarette smoking
  3. Model 3: Model 2 + hypertension, diabetes mellitus, body mass index
  4. *Abbreviation: PY Person-year, HR Hazard ratio, CI Confidence interval
  5. Incidence rate is for the total participants.
  6. HR is for the 4th quartile compared to the 1st quartile.
  7. ** P-value is for β coefficient of multiple linear regression analysis.