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Table 3 Association between quartiles of high-density lipoprotein cholesterol and cardiovascular disease

From: Association between lipoprotein cholesterol and future cardiovascular disease and mortality in older adults: a Korean nationwide longitudinal study

 

Event

Duration (PYs)

Incidence rate

Crude

Model 1

Model 2

Model 3

HR (95% CI)

HR (95% CI)

HR (95% CI)

HR (95% CI)

β x 104 (P-value**)

β x 104 (P-value**)

β x 104 (P-value**)

β x 104 (P-value**)

Cardiovascular event

 Ischemic heart disease

198

204025.6

0.970

0.88 (0.77–1.00)

0.90 (0.80–1.03)

0.90 (0.80–1.03)

0.95 (0.83–1.09)

    

-3.789 (0.057)

-2.804 (0.163)

-2.832 (0.159)

-1.293 (0.585)

 Ischemic brain disease

125

204025.6

0.613

0.95 (0.82–1.12)

0.98 (0.83–1.14)

0.98 (0.84–1.15)

0.94 (0.79–1.12)

    

-0.784 (0.621)

-0.292 (0.855)

-0.262 (0.870)

-0.960 (0.610)

 Total

323

204025.6

1.583

0.91 (0.82–1.00)

0.93 (0.85–1.03)

0.93 (0.85–1.03)

0.95 (0.85–1.05)

    

-4.573 (0.041)

-3.096 (0.164)

-3.094 (0.165)

-2.252 (0.633)

Cardiovascular death

 Ischemic heart disease

45

204058.7

0.221

0.79 (0.61–1.04)

0.84 (0.65–1.10)

0.85 (0.65–1.11)

0.82 (0.60–1.11)

    

-1.543 (0.105)

-1.041 (0.278)

-0.993 (0.301)

-1.237 (0.248)

 Ischemic brain disease

69

204058.7

0.338

1.04 (0.84–1.28)

1.06 (0.86–1.31)

1.06 (0.86–1.31)

1.10 (0.87–1.40)

    

-1.121 (0.223)

-0.881 (0.342)

-0.846 (0.361)

-0.551 (0.591)

 Total

114

204058.7

0.559

0.93 (0.79–1.10)

0.98 (0.83–1.15)

0.98 (0.83–1.15)

0.98 (0.81–1.19)

    

-1.043 (0.491)

-0.312 (0.838)

-0.222 (0.884)

-0.113 (0.947)

  1. Model 1: age, sex
  2. Model 2: Model 1 + cigarette smoking
  3. Model 3: Model 2 + hypertension, diabetes mellitus, body mass index
  4. *Abbreviation: PY Person-year, HR Hazard ratio, CI Confidence interval
  5. Incidence rate is for the total participants.
  6. HR is for the 4th quartile compared to the 1st quartile.
  7. ** P-value is for β coefficient of multiple linear regression analysis.