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Table 1 Clinical characteristics

From: Triglyceride glucose index is a useful marker for predicting subclinical coronary artery disease in the absence of traditional risk factors

 

Total (n = 1250)

Tertile of TyG index

I (lowest) (n = 413)

6.98–8.08

II (n = 424)

8.09–8.47

III (highest) (n = 413)

8.48–10.17

P

Age, years

52.8 ± 6.5

52.3 ± 6.4

52.7 ± 6.6

53.2 ± 6.5

0.133

Age ≥ 65 years, n (%)

75 (6)

20 (4.8)

26 (6.1)

29 (7.9)

0.415

Male, n (%)

586 (46.9)

156 (37.8)

181 (42.7)

249 (60.3)

< 0.001

Systolic BP, mmHg

113.2 ± 10.7

111.6 ± 10.8

112.5 ± 10.4

115.5 ± 10.4

< 0.001

Diastolic BP, mmHg

71.3 ± 8.8

69.9 ± 8.9

70.5 ± 8.9

73.6 ± 8.2

< 0.001

BMI, kg/m2

22.2 ± 1.7

21.7 ± 1.9

22.2 ± 1.6

22.8 ± 1.5

< 0.001

Family history of CAD, n (%)

196 (15.7)

53 (12.8)

63 (14.9)

80 (19.4)

0.030

Framingham risk score

3.9 ± 2.9

2.8 ± 2.4

3.5 ± 2.5

5.3 ± 3.2

< 0.001

Total cholesterol, mg/dL

192.3 ± 25.0

185.5 ± 26.7

193.0 ± 24.2

198.4 ± 22.4

< 0.001

Triglyceride, mg/dL

94.3 ± 48.6

55.9 ± 9.7

82.1 ± 10.8

145.2 ± 52.1

< 0.001

LDL-C, mg/dL

116.1 ± 22.2

107.9 ± 22.3

117.5 ± 21.0

122.9 ± 20.6

< 0.001

HDL-C, mg/dL

60.9 ± 13.2

66.9 ± 13.3

61.7 ± 12.0

54.1 ± 10.9

< 0.001

Creatinine, mg/dL

0.8 ± 0.2

0.8 ± 0.2

0.8 ± 0.2

0.9 ± 0.2

< 0.001

Fasting glucose, mg/dL

96.0 ± 8.8

92.4 ± 7.9

96.2 ± 8.3

99.5 ± 8.9

< 0.001

HbA1C, %

5.4 ± 0.4

5.4 ± 0.4

5.4 ± 0.4

5.5 ± 0.4

< 0.001

Uric acid, mg/dL

4.9 ± 1.2

4.6 ± 1.2

4.9 ± 1.2

5.3 ± 1.2

< 0.001

Categorical CACS, n (%)

    

0.001

 0

1061 (84.9)

370 (89.6)

366 (86.3)

325 (78.7)

 

 1–10

69 (5.5)

16 (3.9)

23 (5.4)

30 (7.3)

 

 11–100

90 (7.2)

18 (4.4)

29 (6.8)

43 (10.4)

 

 101–400

25 (2.0)

6 (1.5)

5 (1.2)

14 (3.4)

 

 > 400

5 (0.4)

3 (0.7)

1 (0.2)

1 (0.2)

 

Any plaque, n (%)

257 (20.6)

61 (14.8)

82 (19.3)

114 (27.6)

< 0.001

Calcified plaque, n (%)

157 (12.6)

38 (9.2)

50 (11.8)

69 (16.7)

0.004

Non-calcified plaque, n (%)

120 (9.6)

27 (6.5)

35 (8.3)

58 (14.0)

0.001

Mixed plaque, n (%)

32 (2.6)

5 (1.2)

9 (2.1)

18 (4.4)

0.013

  1. Values are given as the mean ± standard deviation or number (%)
  2. P-value of < 0.05 was considered significant
  3. BMI Body mass index, BP Blood pressure, CACS Coronary artery calcium score, CAD Coronary artery disease, HbA1C Hemoglobin A1C, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, TyG Triglyceride glucose