The relationship between blood lipids and plasma amyloid beta is depend on blood pressure: a population-based cross-sectional study

Table 6 Multiple linear regression models of blood lipids and plasma Aβ levels stratified by blood pressure

	High blood pressure group (n = 548)						Normal blood pressure group (n = 734)
	Aβ₄₂(pg/ml)			Aβ₄₀(pg/ml)			Aβ₄₂(pg/ml)			Aβ₄₀(pg/ml)
	β	t	P	β	t	P	β	t	P	β	t	P
Model 3
TG	0.661	1.849	0.065	0.618	1.220	0.223	−0.532	−1.609	0.108	−0.224	−0.480	0.631
TC	− 0.442	− 1.273	0.203	− 0.885	− 1.886	0.060	0.666	2.267	0.024	0.084	0.204	0.838
HDL-c	−1.525	− 1.392	0.165	0.503	0.324	0.746	0.100	0.102	0.919	−1.566	−1.130	0.259
ApoE ε4	0.305	0.372	0.710	−0.727	−0.627	0.531	1.207	1.755	0.080	1.083	1.117	0.264
Model 4
TG	0.552	1.685	0.093	0.466	1.006	0.315	−0.423	−1.371	0.171	−0.185	− 0.426	0.670
LDL-c	−0.363	−1.088	0.277	−0.986	−2.090	0.037	0.743	2.558	0.011	0.013	0.031	0.976
HDL-c	−1.942	−1.935	0.053	−0.259	−0.182	0.855	0.689	0.786	0.432	−1.435	−1.160	0.247
ApoE ε4	0.304	0.370	0.711	−0.707	−0.610	0.542	1.203	1.751	0.080	1.093	1.128	0.260

β, the unstandardized regression coefficient
Model 3: adjust for sex, age, education years, smoking, drinking, lack of physical activity, cardiovascular disease, waistline and lip circumference, pulse rate, SBP, DBP, FBG, TC, TG, HDL-c, BMI and ApoE genotype. BMI, body mass index. SBP, systolic blood pressure. DBP, diastolic blood pressure. FBG, fast blood glucose Aβ, amyloid beta. TC, total cholesterol. TG, triglyceride. HDL-c, high-density lipoprotein. LDL-c, low-density lipoprotein. ApoE, apolipoprotein E
Model 4: adjust for sex, age, education years, smoking, drinking, lack of physical activity, cardiovascular disease, waist and lip circumference, pulse rate, SBP, DBP, FGB, LDL-c, TG, HDL-c, BMI and ApoE genotype. BMI, body mass index. SBP, systolic blood pressure. DBP, diastolic blood pressure. FBG, fast blood glucose Aβ, amyloid beta. TC, total cholesterol. TG, triglyceride. HDL-c, high-density lipoprotein. LDL-c, low-density lipoprotein. ApoE, apolipoprotein E

ISSN: 1476-511X