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Table 6 FFAs profiles analysis of significant difference between the NW and OB groups in two nationalities

From: Serum FFAs profile analysis of Normal weight and obesity individuals of Han and Uygur nationalities in China

Nationality

Category

Free fatty acid

Mean ± standard deviation

VIPa

P Valueb

FCc

NW

Obese

Han

Overall

SFAs

C8:0

0.54 ± 0.27

0.91 ± 0.63

1.22

0.015

1.68

C10:0

0.21 ± 0.16

0.37 ± 0.28

1.12

0.013

1.74

C14:0

4.14 ± 2.97

6.21 ± 2.88

1.14

0.013

1.50

ω-6 PUFAs

C18:2

77.53 ± 35.58

112.10 ± 50.99

1.25

0.025

1.45

C20:3

0.86 ± 0.45

1.41 ± 0.95

1.17

0.011

1.64

C20:4

2.53 ± 1.35

3.51 ± 1.51

1.11

0.033

1.39

ω-3 PUFAs

C22:6

2.00 ± 0.86

2.78 ± 1.19

1.20

0.023

1.39

OCFAs

C7:0

0.18 ± 0.225

0.55 ± 0.39

1.66

0.001

3.00

C9:0

2.05 ± 4.16

6.74 ± 5.67

1.45

0.002

3.29

C11:0

0.06 ± 0.11

0.20 ± 0.16

1.59

0.001

3.41

Male

SFAs

C12:0

0.37 ± 0.18

0.64 ± 0.27

1.43

0.023

1.72

C14:0

3.83 ± 2.23

7.18 ± 2.90

1.51

0.013

1.88

ω-6 PUFAs

C18:2

69.45 ± 33.15

125.66 ± 62.21

1.50

0.016

1.81

C20:3

0.73 ± 0.23

1.64 ± 1.22

1.42

0.013

2.25

C20:4

2.25 ± 1.11

3.99 ± 1.34

1.59

0.008

1.77

ω-3PUFAs

C22:6

1.97 ± 0.81

2.98 ± 1.30

1.21

0.049

1.51

Female

SFAs

C8:0

0.47 ± 0.15

0.75 ± 0.31

1.30

0.049

1.61

C10:0

0.18 ± 0.09

0.31 ± 0.15

1.24

0.049

1.69

OCFAs

C7:0

0.18 ± 0.18

0.57 ± 0.30

1.99

0.003

3.15

C9:0

1.35 ± 1.98

7.26 ± 4.69

2.05

0.006

5.37

C11:0

0.04 ± 0.07

0.24 ± 0.14

2.23

0.001

5.17

Uygur

Overall

ω-6 PUFAs

C20:3

0.88 ± 0.64

1.22 ± 0.71

1.24

0.023

1.39

ω-3 PUFAs

C20:5

0.18 ± 0.11

0.31 ± 0.22

1.04

0.020

1.76

Female

OCFAs

C9:0

0.07 ± 0.04

0.16 ± 0.06

1.55

0.014

1.78

 

C19:0

0.03 ± 0.03

0.09 ± 0.04

1.97

0.009

1.94

  1. Abbreviations: SFA saturated fatty acid, MUFA monounsaturated fatty acid, ω-6 PUFA ω-6 polyunsaturated fatty acid, ω-3 PUFA ω-3 polyunsaturated fatty acid, OCFA odd-chain fatty acid, VIP Variable importance in the projection, FC fold change
  2. aThe variable importance in the projection (VIP) was obtained in the OPLS-DA. The values in boldface indicate VIP > 1
  3. bThe P-values were calculated from the nonparametric Mann-Whitney U test. The values in boldface indicate P < 0.05
  4. cThe fold changes (FCs) were calculated from the intra-group means of the FFA levels, with a positive value indicating a relatively higher concentration in the OB group and a negative value indicating a relatively lower concentration compared with the NW group. The numbers in boldface indicate that the absolute FC value is > 1.5
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Lipids in Health and Disease

ISSN: 1476-511X