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Table 4 Parameters in IPGTT in rats fed C or HFS at week 11

From: Correlation between 12α-hydroxylated bile acids and insulin secretion during glucose tolerance tests in rats fed a high-fat and high-sucrose diet

 

C

HFS

Fasting glucose mg/dL

84.1 ± 2.05

89.1 ± 1.99

Glucose AUC mg/dL•h

255.5 ± 9.56

285.5 ± 11.7

Glucose ΔAUC mg/dL•h

82.9 ± 10.3

111.0 ± 11.6

Fasting insulin nM

0.38 ± 0.05

0.53 ± 0.04*

Insulin AUC nM•h

1.09 ± 0.10

1.60 ± 0.06*

Insulin ΔAUC nM•h

0.32 ± 0.06

0.55 ± 0.06*

Relative HOMA-IR

1.00 ± 0.13

1.38 ± 0.13

Fasting leptin μg/mL

120.4 ± 21.7

238.3 ± 20.1*

  1. * Significant difference from the values in C (Student’s t-test, P < 0.05, n = 10 for C, n = 12 for HFS)
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Lipids in Health and Disease

ISSN: 1476-511X