Table 1 Demographic and clinic characteristics of the study population
Total (n = 152,336) | With NAFLD (n = 41,771) | Without NAFLD (n = 110,565) | p | |
|---|---|---|---|---|
Clinical characteristics | ||||
Age, years | 45 (13) | 48 (12) | 44 (14) | <.001 |
Male percentage, % (n) | 54.2% (82,533) | 75.4% (31,510) | 46.1% (51,023) | <.001 |
BMI, kg/m2 | 24.0 (3.3) | 27.1 (2.8) | 22.9 (2.8) | <.001 |
Systolic pressure, mm Hg | 120 (17) | 128 (16) | 117 (17) | <.001 |
Diastolic pressure, mm Hg | 76 (11) | 81 (11) | 74 (10) | <.001 |
Hypertension, % (n) | 19.5% (29,767) | 33.8% (14,129) | 14.1% (15,638) | <.001 |
T2D, % (n) | 3.7% (5623) | 6.9% (2870) | 2.5% (2753) | <.001 |
CAD, % (n) | 1.3% (1920) | 1.8% (733) | 1.1% (1187) | <.001 |
Biochemical parameters | ||||
TBA, μmol/L | 2.0 (3.1–5.0) | 3.4 (2.3–5.4) | 3.0 (1.9–4.8) | <.001 |
AST, U/L | 23 (17) | 26 (14) | 21 (17) | <.001 |
ALT, U/L | 26 (26) | 37 (28) | 22 (24) | <.001 |
BUN, mmol/L | 5.0 (1.4) | 5.2 (1.4) | 5.0 (1.5) | <.001 |
Cr, μmol/L | 67.3 (22.6) | 71.9 (19.0) | 65.6 (23.6) | <.001 |
UA, μmol/L | 312.3 (83.1) | 359.3 (81.2) | 294.6 (75.8) | <.001 |
FBG, mmol/L | 5.04 (1.29) | 5.48 (1.76) | 4.90 (1.01) | <.001 |
OGTT-2 h BG †, mmol/L | 7.10 (3.07) | 7.74 (3.45) | 6.74 (2.77) | <.001 |
TC, mmol/L | 4.66 (0.93) | 4.92 (1.00) | 4.56 (0.88) | <.001 |
HDLC, mmol/L | 1.31 (0.30) | 1.16 (0.24) | 1.37 (0.30) | <.001 |
LDLC, mmol/L | 2.67 (0.77) | 2.81 (0.83) | 2.62 (0.74) | <.001 |
RLP-C, mmol/L | 0.68 (0.61) | 0.95 (0.88) | 0.57 (0.43) | <.001 |
TG, mmol/L | 1.24 (0.86–1.86) | 1.87 (1.33–2.74) | 1.07 (0.78–1.53) | <.001 |