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Table 1 The results of ELISA between Sham, AS and EMPA group

From: Empagliflozin protects against atherosclerosis progression by modulating lipid profiles and sympathetic activity

 

Sham group, n = 6

AS group, n = 6

EMPA group, n = 6

P value

TG

1.56 ± 0.35

4.45 ± 1.18###

2.05 ± 0.58***

< 0.0001

TC

33.37 ± 11.27

68.66 ± 7.94##

53.38 ± 4.28*

< 0.0001

HDL

5.31 ± 1.83

8.57 ± 2.32#

6.49 ± 1.58

0.0549

LDL

6.97 ± 1.67

15.10 ± 2.05##

12.16 ± 0.69*

< 0.0001

IL-1β

60.72 ± 1.70

60.95 ± 2.92

59.32 ± 3.64

0.6401

IL-6

72.48 ± 1.81

83.22 ± 5.79

82.47 ± 8.95

0.0327

IL-10

335.2 ± 24.0

426.2 ± 34.63#

392.3 ± 27.06*

0.0026

Renin

143.4 ± 8.72

156.8 ± 6.24##

147.5 ± 3.81*

0.0208

Ang II

269.6 ± 33.53

287.3 ± 11.96

305.5 ± 9.38

0.0692

ALD

115.8 ± 2.92

127.9 ± 6.20##

111.2 ± 4.23***

0.0003

NE

73.77 ± 5.38

86.87 ± 4.29##

77.94 ± 3.07*

0.0045

NPY

91.82 ± 1.98

98.54 ± 2.62##

89.72 ± 3.93**

0.0026

  1. #P < 0.05, ##P < 0.01 and ###P < 0.001 vs.. sham; *P < 0.05, **P < 0.01 and ***P < 0.001 vs.. AS