Table 1 Patient demographics and laboratory parameters (C-reactive protein, CRP; alanine aminotransferase, ALT; aspartate aminotransferase, AST). Median values and range of the values are shown. Superscript digits were added when the respective information was not available for the whole study group and correspond to the number of patients where these data were documented. Not applicable, na; not determined, nd; *** P < 0.001 for comparison of serum parameters from cirrhotic and non-cirrhotic patients
| Â | Cirrhosis Patients Plasma | Cirrhosis Patients Serum | Non-cirrhosis Patients Serum |
|---|---|---|---|
Number | 38 | 26 | 55 |
Sex (female/male) | 9/29 | 5/21 | 23/32 |
Age (years) | 53 (26–81) | 49 (40–81) | 58 (21–80) |
Child-Pugh score A/B/C/nd | 10/13/15/0 | 8/7/7/4 | na |
MELD score | 9 (6–21) | 8 (6–21) 22 | na |
Ascites: no / little / modest / massive /nd | 4/11/4/19/0 | 6/9/2/8/1 | na |
Variceal size: no / small / large / nd | 6/7/25/0 | 5/4/16/1 | na |
C-reactive protein (mg/L) | 14.4 (1.0–53.5) 35 | 13.9 (2.0–46.7) 20 | nd |
Fibrinogen (mg/dL) | 263 (114–520) 37 | 349 (151–515) 22 | nd |
Antithrombin 3 (%) | 63.7 (23.6–100.0) 34 | 65 (23.6–92.8) 21 | nd |
Factor V (%) | 59 (17–137) 25 | 61 (17–127) 20 | nd |
ALT (U/l) | 38 (4–108) | 38 (7–108) | 32 (16–288) 54 |
AST (U/l) | 30.0 (2–84) | 29 (2–73) | 24 (12–256) 54 |
Albumin (g/L) | 31.2 (1.6–47.0) | 31.5 (1.6–4.1) | 46.8 (31.6–55.6) *** |
Bilirubin (mg/dL) | 1.2 (0.3–8.2) | 1.1 (0.4–3.7) | 0.5 (0.2–2.8) 53 *** |
Quick prothrombin time (%) | 72 (28–100) | 76 (44–100) 22 | nd |
Creatinine (mg/dL) | 1.1 (0.5–4.5) | 1.0 (0.6–4.5) 22 | nd |
LDL (mg/dL) |  60 (6-128) | 35 (17–81) | 112 (44–340)52 *** |