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Table 2 Correlation coefficients of PCSK9 in the different blood compartments of all patients with MELD score, bilirubin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), Quick prothrombin time, antithrombin 3, fibrinogen, factor V and creatinine, which were measured in peripheral blood. Highlighted in yellow are the correlation coefficients in the subgroup of patients with alcoholic disease etiology. Superscript digits indicate number of patients where these data were available. * P < 0.05, ** P < 0.01

From: Proprotein convertase subtilisin/kexin type 9 (PCSK9) levels are not associated with severity of liver disease and are inversely related to cholesterol in a cohort of thirty eight patients with liver cirrhosis

PCSK9 HVP PVP SVP
MELD 0.070 37 0.079 38 0.084 31
−0.126 31 0.008 31 0.094 26
Bilirubin −0.096 38 −0.055 38 − 0.018 31
−0.234 31 − 0.246 31 −0.119 26
AST −0.015 38 0.140 38 0.276 31
−0.165 31 −0.043 31 0.123 26
ALT −0.251 38 −0.094 38 − 0.029 31
−0.342 31 − 0.232 31 −0.086 26
Albumin −0.115 38 −0.030 38 − 0.476 31 **
−0.085 31 0.027 31 −.471 26 *
Quick Prothrombin Time 0.223 38 0.181 38 0.277 31
0.179 31 0.167 31 0.317 26
Antithrombin 3 0.277 34 0.312 34 0.308 27
0.303 29 0.367 29 0.350 24
Fibrinogen 0.134 37 0.127 37 0.224 30
0.215 30 0.215 30 0.336 25
Factor V 0.023 25 0.064 25 0.169 20
−0.087 22 −0.046 22 0.020 18
Creatinine 0.002 38 0.098 38 0.078 31
0.048 31 0.130 31 0.173 26
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