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Table 5 Median, minimum (Min) and maximum (Max) values of serum sphingomyelin (SM) species in patients with PCSK9 levels below and above the median level. * P < 0.05

From: Proprotein convertase subtilisin/kexin type 9 (PCSK9) levels are not associated with severity of liver disease and are inversely related to cholesterol in a cohort of thirty eight patients with liver cirrhosis

SM species (μmol/L) SVP PCSK9 below the median level
(16 patients)
SVP PCSK9 above the median level
(15 patients)
P-value
  Median Min Max Median Min Max  
SM 14:0 4.9 2.7 9.0 4.4 2.0 5.8  
SM 15:0 2.9 1.5 4.7 2.3 0.9 3.9  
SM16:1 11.2 5.7 22.3 8.0 4.7 16.6  
SM16:0 69.2 40.3 126.6 58.6 26.3 86.3  
SM 18:2 0.2 0.0 0.9 0.3 0.0 0.6  
SM 18:1 5.8 2.4 12.2 3.6 1.8 9.2  
SM 18:0 9.8 3.8 18.7 6.2 0.0 12.4 *
SM 20:1 3.0 1.4 5.3 2.3 1.4 3.6 *
SM 20:0 6.1 2.2 9.8 6.9 2.6 11.3  
SM 22:2 2.1 0.0 3.9 2.1 0.0 4.5  
SM 22:1 12.8 6.8 21.4 10.3 0.0 18.6  
SM 22:0 11.2 5.2 20.3 9.2 4.9 16.1  
SM 23:1 5.9 2.5 12.3 4.5 2.8 9.0  
SM 23:0 3.7 1.1 8.8 2.9 1.7 6.2  
SM 24:3 1.6 0.0 3.6 1.5 0.3 4.3  
SM 24:2 20.9 10.8 36.6 15.9 10.7 24.2 *
SM 24:1 50.1 36.1 95.0 41.8 18.4 71.2 *
SM 24:0 7.1 4.7 13.6 6.6 3.3 10.9  
SM 26:2 0.5 0.0 1.0 0.3 0.0 1.1  
SM 26:1 0.5 0.0 1.1 0.3 0.0 0.8  
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