Table 2 Enzymes and inhibitors of the electron transport chain (ETC)
From: The impact of reactive oxygen species in the development of cardiometabolic disorders: a review
Complex | Enzymes | Inhibitors |
|---|---|---|
Complex I | NADH-ubiquinone oxidoreductase | Rotenone, Amobarbital (Amytal), Demerol, Piericidin, |
Complex II | Succinate- ubiquinone oxidoreductase | Thenoyltrifluoroacetne (TTFA), Malonate oxaloacetate, Diazoxide |
Complex III | Ubiquinone cytochrome-c oxidoreductase | Antimycin A, Myxothiazol, Stigmatellin |
Complex IV | Cytochrome-c oxidase | Cyanide, Carbon monoxide, Azide, Hydrogen sulphide |
Complex V | ATP synthase | Oligomycin A, Diyclo hexyl carbo dimide (DCCD) |