Fig. 1From: Familial hypertriglyceridemia: an entity with distinguishable features from other causes of hypertriglyceridemiaProposed physiopathological mechanisms that may contributed to the genesis of familial hypertriglyceridemia. Inhibition of LPL orchestrated by FGF21 and ANGPTL3, both of which are regulated by CHREBP. This results in alterations in the composition of VLDL particles with numbers remaining unchangedBack to article page