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Fig. 12 | Lipids in Health and Disease

Fig. 12

From: Identification of lipidomic profiles associated with drug-resistant prostate cancer cells

Fig. 12

a Western blot for Lipin-1 (~ 125 kDa) and GAPDH expression (~ 36 kDa) in non-cancerous prostate cells (PNT2 and RWPE-1), hormone-sensitive (LNCaP and 22RV1), castration-resistant (CR) (PC-3 and DU-145), Docetaxel resistant (DR) (PC3-RX and DU145-DR) prostate cells and hepatocellular carcinoma (HepG2) cells (positive control). Immunoblots are representative of at least 3 (n = 3) separate experiments using 3 separate passages. b Densitometry of Lipin-1 protein normalized to GAPDH within non-cancerous prostate cells (blue), hormone-sensitive (orange), castration-resistant (CR) (green), Docetaxel resistant (DR) (red) prostate, and hepatocellular carcinoma (black) cell lines

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