Skip to main content

Table 3 Logistic regression models assessing the associations of TG and lipid ratios with increased UACR

From: Triglycerides to high-density lipoprotein cholesterol ratio is superior to triglycerides and other lipid ratios as an indicator of increased urinary albumin-to-creatinine ratio in the general population of China: a cross-sectional study

 

Unadjusted

Model 1

Model 2

Model 3

Model 4

OR(95%CI)

P value

OR(95%CI)

P value

OR(95%CI)

P value

OR(95%CI)

P value

OR(95%CI)

P value

Female

 TG

  Q1

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

  Q2

1.29(1.16–1.44)

< 0.001

1.11(0.99–1.24)

0.083

1.06(0.94–1.19)

0.339

0.99(0.88–1.11)

0.862

0.99(0.88–1.11)

0.819

  Q3

1.65(1.48–1.83)

< 0.001

1.26(1.13–1.41)

< 0.001

1.14(1.02–1.28)

0.022

1.03(0.92–1.16)

0.619

1.02(0.91–1.15)

0.688

  Q4

2.19(1.98–2.43)

< 0.001

1.64(1.47–1.83)

< 0.001

1.41(1.26–1.57)

< 0.001

1.16(1.03–1.30)

0.013

1.15(1.02–1.29)

0.021

 TG/HDL-C

  Q1

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

  Q2

1.59(1.42–1.78)

< 0.001

1.33(1.18–1.49)

< 0.001

1.27(1.13–1.43)

< 0.001

1.20(1.07–1.36)

0.002

1.20(1.07–1.35)

0.003

  Q3

1.87(1.67–2.08)

< 0.001

1.40(1.24–1.57)

< 0.001

1.27(1.13–1.43)

< 0.001

1.13(1.00–1.27)

0.044

1.13(1.00–1.27)

0.051

  Q4

2.55(2.29–2.83)

< 0.001

1.81(1.62–2.03)

< 0.001

1.58(1.41–1.78)

< 0.001

1.29(1.15–1.46)

< 0.001

1.28(1.13–1.44)

< 0.001

 Non-HDL-C/HDL-C

  Q1

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

  Q2

1.09(0.99–1.21)

0.088

1.08(0.97–1.20)

0.165

1.03(0.92–1.14)

0.644

0.98(0.88–1.10)

0.755

0.98(0.88–1.10)

0.735

  Q3

1.17(1.06–1.30)

0.002

1.17(1.06–1.31)

0.003

1.08(0.97–1.21)

0.147

0.98(0.88–1.09)

0.704

0.97(0.87–1.09)

0.642

  Q4

1.42(1.28–1.56)

< 0.001

1.51(1.36–1.68)

< 0.001

1.34(1.20–1.49)

< 0.001

1.14(1.02–1.27)

0.024

1.13(1.01–1.26)

0.034

Male

 TG

  Q1

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

  Q2

1.07(0.90–1.28)

0.454

1.01(0.85–1.21)

0.898

0.90(0.75–1.08)

0.267

0.85(0.70–1.03)

0.093

0.85(0.70–1.03)

0.092

  Q3

1.38(1.17–1.64)

< 0.001

1.32(1.11–1.57)

0.001

1.06(0.89–1.27)

0.520

0.97(0.81–1.17)

0.742

0.97(0.80–1.16)

0.704

  Q4

1.60(1.36–1.89)

< 0.001

1.66(1.40–1.97)

< 0.001

1.19(0.99–1.43)

0.058

1.06(0.87–1.28)

0.578

1.05(0.87–1.26)

0.643

 TG/HDL-C

  Q1

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

  Q2

1.20(1.00–1.44)

0.046

1.17(0.97–1.40)

0.100

1.04(0.86–1.25)

0.702

0.98(0.81–1.19)

0.858

0.98(0.81–1.19)

0.831

  Q3

1.47(1.23–1.74)

< 0.001

1.40(1.17–1.67)

< 0.001

1.14(0.94–1.37)

0.176

1.05(0.87–1.27)

0.626

1.04(0.86–1.26)

0.671

  Q4

1.86(1.58–2.20)

< 0.001

1.90(1.60–2.27)

< 0.001

1.41(1.17–1.70)

< 0.001

1.25(1.03–1.51)

0.024

1.24(1.02–1.50)

0.032

 Non-HDL-C/HDL-C

  Q1

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

1.00(reference)

 

  Q2

1.05(0.89–1.25)

0.546

1.08(0.91–1.29)

0.358

0.97(0.81–1.15)

0.704

0.94(0.79–1.13)

0.528

0.94(0.79–1.13)

0.506

  Q3

1.05(0.89–1.24)

0.591

1.12(0.95–1.33)

0.184

0.95(0.79–1.13)

0.552

0.87(0.73–1.05)

0.144

0.87(0.72–1.04)

0.131

  Q4

1.29(1.10–1.52)

0.002

1.57(1.32–1.85)

< 0.001

1.21(1.01–1.45)

0.036

1.11(0.92–1.33)

0.287

1.10(0.91–1.32)

0.329

  1. Model 1: adjusted for center, age.
  2. Model 2: additionally adjusted for ALT, γ-GGT, BMI, smoking, drinking, cardiovascular disease, eGFR.
  3. Model 3: additionally adjusted for HbA1c, SBP, DBP, pulse and use of anti-diabetic medication.
  4. Model 4: additionally adjusted for HOMA-IR.
  5. Abbreviations: UACR urinary albumin-creatinine ratio; OR odds ratio; CI confidence interval; TG triglyceride; HDL-C high-density lipoprotein cholesterol; non-HDL-C non-high-density lipoprotein cholesterol; eGFR estimated glomerular filtration rate; ALT alanine transaminase; γ-GGT γ-glutamyl transpeptidase; BMI body mass index; SBP systolic blood pressure; DBP diastolic blood pressure; HbA1c hemoglobin A1c; HOMA-IR homeostasis model assessment of insulin resistance
Back to article page

Lipids in Health and Disease

ISSN: 1476-511X