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Table 4 The logistic regression analyses evaluating the correlation between TG/HDL-C and increased UACR in subgroups

From: Triglycerides to high-density lipoprotein cholesterol ratio is superior to triglycerides and other lipid ratios as an indicator of increased urinary albumin-to-creatinine ratio in the general population of China: a cross-sectional study

Variable

Q1

Q2

P value

Q3

P value

Q4

P value

  

OR (95% CI)

OR (95% CI)

OR (95% CI)

Female

 Blood glucosea

  Normal

1.00(reference)

0.99(0.77–1.27)

0.931

1.12(0.86–1.45)

0.396

1.13(0.85–1.51)

0.404

  Prediabetes

1.00(reference)

1.34(1.13–1.58)

0.001

1.18(0.99–1.39)

0.060

1.31(1.10–1.56)

0.003

  Diabetes

1.00(reference)

1.06(0.83–1.37)

0.632

1.03(0.81–1.31)

0.820

1.22(0.97–1.54)

0.092

 Blood pressureb

  Normal

1.00(reference)

1.01(0.81–1.26)

0.915

0.97(0.77–1.22)

0.774

0.92(0.71–1.18)

0.496

  Prehypertension

1.00(reference)

1.37(1.12–1.68)

0.002

1.22(0.99–1.49)

0.057

1.48(1.21–1.81)

< 0.001

  Hypertension

1.00(reference)

1.13(0.92–1.39)

0.234

1.12(0.92–1.36)

0.270

1.32(1.09–1.60)

0.005

 BMIc

  BMI < 18.5

1.00(reference)

0.92(0.50–1.70)

0.797

0.58(0.24–1.43)

0.237

  

  18.5 ≤ BMI < 24

1.00(reference)

1.23(1.05–1.45)

0.012

1.09(0.92–1.30)

0.309

1.25(1.05–1.49)

0.014

  24 ≤ BMI < 28

1.00(reference)

1.19(0.95–1.47)

0.128

1.16(0.94–1.43)

0.179

1.37(1.11–1.68)

0.003

  BMI ≥ 28

1.00(reference)

1.18(0.80–1.74)

0.395

1.31(0.92–1.89)

0.139

1.37(0.96–1.97)

0.083

 Aged

   ≤ 55

1.00(reference)

1.06(0.87–1.28)

0.575

1.10(0.91–1.34)

0.339

1.26(1.03–1.55)

0.023

   > 55

1.00(reference)

1.32(1.14–1.55)

< 0.001

1.17(1.00–1.36)

0.050

1.28(1.10–1.49)

0.001

Male

 Blood glucosea

  Normal

1.00(reference)

1.12(0.68–1.84)

0.655

0.85(0.49–1.48)

0.573

0.98(0.55–1.78)

0.956

  Prediabetes

1.00(reference)

0.94(0.70–1.24)

0.643

0.98(0.73–1.32)

0.906

1.12(0.83–1.52)

0.456

  Diabetes

1.00(reference)

0.96(0.71–1.30)

0.787

1.17(0.87–1.58)

0.300

1.36(1.01–1.83)

0.041

 Blood pressureb

   Normal

1.00(reference)

1.05(0.66–1.67)

0.855

1.14(0.71–1.85)

0.585

1.36(0.82–2.26)

0.240

  Prehypertension

1.00(reference)

0.98(0.71–1.37)

0.923

0.97(0.70–1.35)

0.867

1.10(0.79–1.54)

0.574

  Hypertension

1.00(reference)

0.93(0.71–1.22)

0.600

0.98(0.74–1.29)

0.871

1.18(0.90–1.54)

0.241

 BMIc

  BMI < 18.5

1.00(reference)

1.14(0.35–3.70)

0.823

0.28(0.03–3.06)

0.298

  

  18.5 ≤ BMI < 24

1.00(reference)

0.93(0.71–1.23)

0.621

1.01(0.76–1.36)

0.930

0.92(0.66–1.27)

0.598

  24 ≤ BMI < 28

1.00(reference)

1.13(0.81–1.58)

0.476

1.24(0.90–1.71)

0.198

1.58(1.15–2.17)

0.005

  BMI ≥ 28

1.00(reference)

0.86(0.47–1.55)

0.610

0.96(0.55–1.69)

0.898

1.32(0.76–2.28)

0.322

 Aged

   ≤ 55

1.00(reference)

1.20(0.77–1.88)

0.422

1.04(0.67–1.62)

0.852

1.19(0.78–1.84)

0.419

   > 55

1.00(reference)

0.91(0.74–1.13)

0.410

1.03(0.83–1.28)

0.762

1.20(0.97–1.49)

0.101

  1. Model a: center, age, ALT, γ-GGT, BMI, eGFR, cardiovascular disease, smoking, drinking, SBP, DBP, pulse, use of anti-diabetic medication, HOMA-IR.
  2. Model b: center, age, ALT, γ-GGT, BMI, eGFR, cardiovascular disease, smoking, drinking, pulse, HbA1c, use of anti-diabetic medication, HOMA-IR.
  3. Model c: center, age, ALT, γ-GGT, eGFR, cardiovascular disease, smoking, drinking, SBP, DBP, pulse, HbA1c, use of anti-diabetic medication, HOMA-IR.
  4. Model d: center, ALT, γ-GGT, BMI, eGFR, cardiovascular disease, smoking, drinking, SBP, DBP, pulse, HbA1c, use of anti-diabetic medication, HOMA-IR.
  5. Abbreviations: TG triglyceride; HDL-C, high-density lipoprotein cholesterol; UACR urinary albumin-creatinine ratio; OR odds ratio; CI confidence interval; eGFR estimated glomerular filtration rate; ALT alanine transaminase; γ-GGT γ-glutamyl transpeptidase; BMI body mass index; SBP systolic blood pressure; DBP diastolic blood pressure; HbA1c hemoglobin A1c; HOMA-IR homeostasis model assessment of insulin resistance
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Lipids in Health and Disease

ISSN: 1476-511X