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Table 2 Diagnostic accuracy of the LSM value in detecting each degree of fibrosis

From: Performance of liver stiffness measurements obtained with FibroScan is affected by glucose metabolism in patients with nonalcoholic fatty liver disease

Fibrosis Stage

Cut-off value† (kPa)

AUROC

95% CI

Se (%)

Sp (%)

PPV (%)

NPV (%)

P value

≥1

6.3

0.793

0.695–0.871

71.1

75.0

96.7

20.0

0.0002

≥2

7.6

0.764

0.663–0.846

68.0

68.3

72.3

63.6

< 0.0001

≥3

8.3

0.837

0.744–0.906

80.0

76.1

48.5

93.1

< 0.0001

≥4

13.8

0.902

0.822–0.955

80.0

94.2

44.4

98.8

< 0.0001

  1. †Cut-off value was optimized by the maximal sum of sensitivity and specificity
  2. * Abbreviations: AUROC area under the receiver operator characteristic curve, 95% CI 95% confidence interval, Se sensitivity, Sp specificity, PPV positive predictive value, NPV negative predictive value
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Lipids in Health and Disease

ISSN: 1476-511X