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Table 3 Univariate and Multivariate linear regression analysis of metabolic indicators associated with LSM value

From: Performance of liver stiffness measurements obtained with FibroScan is affected by glucose metabolism in patients with nonalcoholic fatty liver disease

Variable

Univariate linear regression

Multivariate linear regression†

Standardized coefficients (β)

P value

Standardized coefficients (β)

P value

Age

0.231

0.027

–

–

BMI

0.222

0.034

0.160

0.092

hypertension

0.211

0.045

–

–

Fasting glucose

0.222

0.034

–

–

2 h glucose

0.168

0.128

–

–

HbA1c

0.143

0.182

0.205

0.026

Triglycerides

0.023

0.834

–

–

Total cholesterol

0.010

0.928

–

–

LDL cholesterol

0.031

0.780

–

–

HDL cholesterol

0.035

0.748

–

–

ALT

0.150

0.158

0.192

0.047

AST

0.229

0.030

–

–

Fibrosis

0.617

< 0.001

0.502

< 0.001

Inflammation

0.276

0.009

–

–

Ballooning

0.288

0.006

–

–

  1. †The variables with P < 0.2 in the univariate regression were included in the multivariate linear regression. The LSM value served as the dependent variable, and age, BMI, hypertension, fasting glucose, 2 h glucose, HbA1c, AST and ALT served as the independent variables after adjustment for liver fibrosis, ballooning and inflammation
  2. * Abbreviations: BMI body mass index, HbA1c haemoglobin A1c, ALT alanine aminotransferase, AST aspartate aminotransferase