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Table 4 LSM cut-off value in detecting liver fibrosis stage ≥2 grouped by metabolic indicators with consistent sensitivity/specificity

From: Performance of liver stiffness measurements obtained with FibroScan is affected by glucose metabolism in patients with nonalcoholic fatty liver disease

Subgroup

Cut-off value† (kPa)

Se (%)

Sp (%)

PPV (%)

NPV (%)

BMI < 30 kg/m2

6.2

81.5

50.0

59.5

75.0

BMI ≥30 kg/m2

7.5

81.8

63.6

81.8

63.6

HbA1c < 7%

7.7

61.5

80.00

76.2

66.7

HbA1c ≥7%

8.3

60.9

80.00

82.4

57.1

  1. †Cut-off value was determined when the sensitivity or specificity were consistent between subgroups
  2. * Abbreviations: 95% CI 95% confidence interval, Se sensitivity, Sp specificity, PPV positive predictive value, NPV negative predictive value