Table 1 Binding constants (KD) determined for 5 different phospholipid forms against 504B3
Lysophospholipid | KD from FSA ± SD (95% CI) | Bmax (95% CI) | R2 |
|---|---|---|---|
18:1 LPA | 3.7 ± 2.8 nM (2.1 to 9.0) | 0.17 (0.14 to 0.25) | 0.83 |
18:1 PA | 3.3 ± 2.7 nM (1.5 to 6.4) | 0.15 (0.12 to 0.17) | 0.81 |
18:1 LPC | 8.5 ± 2.6 nM (5.3 to 13.5) | 0.14 (0.12 to 0.16) | 0.90 |
16:0 LPA | > 30 nM (undetermineda) | 0.39 (undetermineda) | 0.94 |
18:1 S1P | ~ 0 | – | – |