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Table 2 Data analysis for the human serum samples. The levels of BMI, glucose, insulin, HOMA value, Twist1, Twist2, and PPARĪ³ were recorded. Statistical analysis was performed using ANOVA. Pā€‰<ā€‰0.05 was considered to indicate a significant difference

From: TWIST2 and the PPAR signaling pathway are important in the progression of nonalcoholic steatohepatitis

Parameter

BMI (Xā€‰Ā±ā€‰SD)

glucose (mmol/L,āˆ’Xā€‰Ā±ā€‰SD)

insulin (mIU/L, āˆ’Xā€‰Ā±ā€‰SD)

HOMA (āˆ’Xā€‰Ā±ā€‰SD)

Twist1 concentration (pg/mL, āˆ’Xā€‰Ā±ā€‰SD)

Twist2 concentration (pg/mL, āˆ’Xā€‰Ā±ā€‰SD)

PPARĪ³ concentration (mmol/L, āˆ’Xā€‰Ā±ā€‰SD)

Group

healthy control

22.42 Ā± 2.54ā–”, ā˜†, ā€»

4.98 Ā± 0.50ā–”, ā˜†, ā€»

6.93 Ā± 3.12ā–”, ā˜†, ā€»

1.54 Ā± 0.74ā–”, ā˜†, ā€»

287.54 Ā± 264.02ā–”, ā˜†

2.63 Ā± 2.26

258.88 Ā± 241.26

mild fatty liver

26.32 Ā± 2.45ā–³, ā˜†, ā€»

5.35 Ā± 0.50ā–³, ā˜†, ā€»

9.19 Ā± 4.18ā–³, ā˜†, ā€»

2.19 Ā± 1.02ā–³, ā˜†, ā€»

176.62 Ā± 166.08ā–³, ā˜†, ā€»

2.00 Ā± 1.34ā–³

227.84 Ā± 208.65

moderate fatty liver

28.25 Ā± 2.75ā–³, ā–”, ā€»

5.92 Ā± 1.59ā–³, ā–”, ā€»

11.82 Ā± 6.77ā–³, ā–”, ā€»

3.15 Ā± 2.07ā–³, ā–”, ā€»

380.39 Ā± 331.48ā–³, ā–”, ā€»

2.04 Ā± 1.37ā–³

216.30 Ā± 177.04

severe fatty liver

31.30 Ā± 3.31ā–³, ā–”, ā˜†

6.29 Ā± 1.93ā–³, ā–”, ā˜†

15.29 Ā± 7.66ā–³, ā–”, ā˜†

4.20 Ā± 2.23ā–³, ā–”, ā˜†

279.26 Ā± 238.77ā–”, ā˜†

2.06 Ā± 1.16ā–³

225.72 Ā± 182.68

  1. BMI: body mass index, kg/m2, HOMA homeostasis model assessment; ā–³Pā€‰<ā€‰0.05, compared with healthy controls; ā–”Pā€‰<ā€‰0.05, compared with mild fatty liver; āœ©Pā€‰<ā€‰0.05, compared with moderate fatty liver; ā€»Pā€‰<ā€‰0.05, compared with severe fatty liver