Table 1 Baseline characteristics of the cohort participants
Characteristics | Overall (n = 14,911) | Male (n = 7838) | Female (n = 7073) | P value |
|---|---|---|---|---|
Age (years) | 52.41 ± 14.80 | 53.11 ± 15.48 | 51.63 ± 13.97 | < 0.01 |
BMI (kg/ m2) | 24.99 ± 3.58 | 25.80 ± 3.33 | 24.09 ± 3.62 | < 0.01 |
 Lean | 362 (2.4%) | 95 (1.2%) | 267 (3.8%) |  |
 Overweight | 6093 (40.9%) | 3759 (48.0%) | 2334 (33.0%) |  |
 Obesity | 2841 (19.1%) | 1830 (23.3%) | 1011 (14.3%) |  |
WHR | 0.85 ± 0.07 | 0.89 ± 0.06 | 0.80 ± 0.06 | < 0.01 |
 High | 6292 (42.4%) | 2923 (37.3%) | 3369 (47.6%) |  |
ALT (IU/L) | 22.52 ± 17.74 | 26.11 ± 20.27 | 18.55 ± 13.34 | < 0.01 |
 High | 1322 (8.9%) | 969 (12.4%) | 353 (5.0%) |  |
AST (IU/L) | 22.29 ± 9.74 | 23.27 ± 10.94 | 21.19 ± 8.08 | < 0.01 |
 High | 456 (3.1%) | 297 (3.8%) | 159 (2.2%) |  |
CREA (μmol/L) | 65.98 ± 17.87 | 75.36 ± 17.83 | 55.58 ± 10.74 | < 0.01 |
 High | 381 (2.6%) | 303 (3.9%) | 78 (1.1%) |  |
UA (μmol/L) | 316.85 ± 90.69 | 363.21 ± 83.64 | 265.48 ± 67.60 | < 0.01 |
 High | 2535 (17.0%) | 1857 (23.7%) | 678 (9.6%) |  |
Hcy (μmol/L) | 13.92 ± 8.15 | 16.37 ± 9.66 | 11.22 ± 4.76 | < 0.01 |
 High | 3698 (24.8%) | 2901 (37.0%) | 797 (11.3%) |  |
TG (mmol/L) | 1.65 ± 1.44 | 1.88 ± 1.72 | 1.39 ± 1.00 | < 0.01 |
 High | 2657 (17.8%) | 1828 (23.3%) | 829 (11.7%) |  |
TC (mmol/L) | 4.85 ± 0.94 | 4.79 ± 0.92 | 4.92 ± 0.96 | < 0.01 |
 High | 1118 (7.5%) | 481 (6.1%) | 637 (9.0%) |  |
LDL-C (mmol/L) | 2.97 ± 0.83 | 2.96 ± 0.80 | 2.98 ± 0.85 | 0.207 |
 High | 1199 (8.0%) | 559 (7.1%) | 640 (9.0%) |  |
HDL-C (mmol/L) | 1.50 ± 0.38 | 1.39 ± 0.35 | 1.63 ± 0.38 | < 0.01 |
 Low | 1310 (8.8%) | 1029 (13.1%) | 281 (4.0%) |  |
Glu (mmol/L) | 5.59 ± 1.41 | 5.75 ± 1.53 | 5.41 ± 1.24 | < 0.01 |
 High | 2458 (16.5%) | 1619 (20.7%) | 839 (11.9%) |  |