Skip to main content

Table 1 Baseline characteristics of the cohort participants

From: Gender differences in risk factors for high plasma homocysteine levels based on a retrospective checkup cohort using a generalized estimating equation analysis

Characteristics Overall
(n = 14,911)
Male
(n = 7838)
Female
(n = 7073)
P value
Age (years) 52.41 ± 14.80 53.11 ± 15.48 51.63 ± 13.97 < 0.01
BMI (kg/ m2) 24.99 ± 3.58 25.80 ± 3.33 24.09 ± 3.62 < 0.01
 Lean 362 (2.4%) 95 (1.2%) 267 (3.8%)  
 Overweight 6093 (40.9%) 3759 (48.0%) 2334 (33.0%)  
 Obesity 2841 (19.1%) 1830 (23.3%) 1011 (14.3%)  
WHR 0.85 ± 0.07 0.89 ± 0.06 0.80 ± 0.06 < 0.01
 High 6292 (42.4%) 2923 (37.3%) 3369 (47.6%)  
ALT (IU/L) 22.52 ± 17.74 26.11 ± 20.27 18.55 ± 13.34 < 0.01
 High 1322 (8.9%) 969 (12.4%) 353 (5.0%)  
AST (IU/L) 22.29 ± 9.74 23.27 ± 10.94 21.19 ± 8.08 < 0.01
 High 456 (3.1%) 297 (3.8%) 159 (2.2%)  
CREA (μmol/L) 65.98 ± 17.87 75.36 ± 17.83 55.58 ± 10.74 < 0.01
 High 381 (2.6%) 303 (3.9%) 78 (1.1%)  
UA (μmol/L) 316.85 ± 90.69 363.21 ± 83.64 265.48 ± 67.60 < 0.01
 High 2535 (17.0%) 1857 (23.7%) 678 (9.6%)  
Hcy (μmol/L) 13.92 ± 8.15 16.37 ± 9.66 11.22 ± 4.76 < 0.01
 High 3698 (24.8%) 2901 (37.0%) 797 (11.3%)  
TG (mmol/L) 1.65 ± 1.44 1.88 ± 1.72 1.39 ± 1.00 < 0.01
 High 2657 (17.8%) 1828 (23.3%) 829 (11.7%)  
TC (mmol/L) 4.85 ± 0.94 4.79 ± 0.92 4.92 ± 0.96 < 0.01
 High 1118 (7.5%) 481 (6.1%) 637 (9.0%)  
LDL-C (mmol/L) 2.97 ± 0.83 2.96 ± 0.80 2.98 ± 0.85 0.207
 High 1199 (8.0%) 559 (7.1%) 640 (9.0%)  
HDL-C (mmol/L) 1.50 ± 0.38 1.39 ± 0.35 1.63 ± 0.38 < 0.01
 Low 1310 (8.8%) 1029 (13.1%) 281 (4.0%)  
Glu (mmol/L) 5.59 ± 1.41 5.75 ± 1.53 5.41 ± 1.24 < 0.01
 High 2458 (16.5%) 1619 (20.7%) 839 (11.9%)  
  1. Abbreviations: BMI body mass index, WHR waist to hip ratio, ALT alanine aminotransferase, AST aspartate aminotransferase, CREA creatinine, UA uric acid, Hcy homocysteine, TG total triglyceride, TC total cholesterol, LDL-C low density lipoprotein- cholesterol, HDL-C high density lipoprotein-cholesterol, Glu glucose