From: Malnutrition affects cholesterol paradox in coronary artery disease: a 41,229 Chinese cohort study
Characteristica | Overall (N = 41,229) | LDL-C < 1.8 mmol/L (N = 4863) | LDL-C ≥ 1.8 mmol/L (N = 36,366) | P value |
---|---|---|---|---|
Demographic characteristics | ||||
Age, years | 62.9 (10.6) | 64.4 (10.8) | 62.8 (10.6) | < 0.001 |
Age ≥ 75 years, n (%) | 6036 (14.6) | 929 (19.1) | 5107 (14.0) | < 0.001 |
Male, n (%) | 30,897 (74.9) | 3725 (76.6) | 27,172 (74.7) | 0.005 |
Coexisting conditions | ||||
PCI, n (%) | 30,415 (73.8) | 3433 (70.6) | 26,982 (74.2) | < 0.001 |
AMI, n (%) | 9182 (22.3) | 805 (16.6) | 8377 (23.0) | < 0.001 |
CHF, n (%) | 3902 (9.5) | 409 (8.4) | 3493 (9.6) | 0.008 |
Hypertension, n (%) | 23,217 (56.3) | 3020 (62.1) | 20,197 (55.5) | < 0.001 |
Diabetes mellitus, n (%) | 11,097 (26.9) | 1623 (33.4) | 9474 (26.1) | < 0.001 |
CKD, n (%) | 8635 (21.9) | 1154 (24.8) | 7481 (21.5) | < 0.001 |
Atrial fibrillation, n (%) | 939 (2.3) | 133 (2.7) | 806 (2.2) | 0.026 |
COPD, n (%) | 348 (0.8) | 54 (1.1) | 294 (0.8) | 0.038 |
Stroke, n (%) | 2340 (5.7) | 347 (7.1) | 1993 (5.5) | < 0.001 |
Anaemia, n (%) | 12,922 (32.3) | 2079 (44.0) | 10,843 (30.7) | < 0.001 |
Laboratory examination | ||||
Haematocrit | 0.40 (0.05) | 0.38 (0.05) | 0.40 (0.05) | < 0.001 |
Lymphocyte, 109/L | 1.94 (0.71) | 1.95 (0.71) | 1.83 (0.69) | < 0.001 |
Total cholesterol, mmol/L | 4.60 (1.21) | 4.78 (1.13) | 3.24 (0.91) | < 0.001 |
HDL-C, mmol/L | 1.00 (0.26) | 1.01 (0.26) | 0.93 (0.30) | < 0.001 |
LDL-C, mmol/L | 2.85 (0.98) | 1.47 (0.26) | 3.04 (0.88) | < 0.001 |
Triglyceride, mmol/L | 1.67 (1.23) | 1.67 (1.09) | 1.68 (1.96) | 0.304 |
Albumin, g/L | 36.29 (4.25) | 36.36 (4.22) | 35.74 (4.44) | < 0.001 |
Medicine | ||||
RASi, n (%) | 20,082 (49.6) | 2199 (46.5) | 17,883 (50.00) | < 0.001 |
β-blocker, n (%) | 32,652 (80.6) | 3776 (79.8) | 28,876 (80.7) | 0.131 |
Statins, n (%) | 38,300 (94.6) | 4396 (92.9) | 33,904 (94.8) | < 0.001 |
Events | ||||
All-cause death, n (%) | 5257 (12.8) | 778 (16.0) | 4479 (12.3) | < 0.001 |