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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Elucidation of SIRT-1/PGC-1α-associated mitochondrial dysfunction and autophagy in nonalcoholic fatty liver disease

Fig. 1

Effect of HFD for 8 weeks on liver steatosis, SIRT-1 and PGC-1ɑ mRNA level and protein expression of SIRT-1, PGC-1ɑ, PPAR-ɑ, p62, Beclin-1. a The liver pathology of mice in the two groups. b Lipid deposition in liver tissues. c The mRNA expression level of SIRT-1 and PGC-1ɑ. d The protein expression of SIRT-1, PGC-1a, PPAR-ɑ, p62 and Beclin-1 was analyzed and quantified. *P < 0.05, **P < 0.01, vs. CON. Original magnification: × 200, × 400

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