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Table 1 General and hepatic parameters in control mice (CON) and high-fat-diet (HFD) mice

From: Elucidation of SIRT-1/PGC-1α-associated mitochondrial dysfunction and autophagy in nonalcoholic fatty liver disease

 

CON

HFD

A. General and hepatic parameters

 Initial body weight (g)

14.49 ± 0.55

14.56 ± 0.41

 Final body weight (g)

29.38 ± 5.58

43.45 ± 5.22**

 Net weight gain (g)

14.89 ± 5.60

28.89 ± 4.97**

 Liver weight (g)

1.20 ± 0.16

2.08 ± 0.47**

B. Food and Energy intake

 Dietary intake (g/day)

3.64 ± 0.37

3.66 ± 0.41

 Energy intake (kcal/day)

14.64 ± 0.68

18.29 ± 1.83**

C. Serum parameters

 TC (mM)

1.39 ± 0.16

2.98 ± 0.38**

 TG (mM)

1.64 ± 0.23

3.95 ± 0.54**

 AST (U/L)

148.14 ± 13.40

180.24 ± 10.08**

 ALT (U/L)

64.14 ± 5.56

74.84 ± 9.05*

 Blood glucose (mg/dL)

122.68 ± 12.30

174.83 ± 19.31**

 Insulin (μU/mL)

5.90 ± 1.95

26.61 ± 3.67**

D. Enzyme activity in liver

 MDA (nmol/g)

37.40 ± 7.10

74.92 ± 9.59**

 SOD (U/g)

78.92 ± 7.75

46.32 ± 6.50**

  1. Values are presented as mean ± SD (n = 6). Data were analyzed by one-way analysis ANOVA. *, ** represents significance from the control group at P < 0.05, P < 0.01