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Table 1 General and hepatic parameters in control mice (CON) and high-fat-diet (HFD) mice

From: Elucidation of SIRT-1/PGC-1α-associated mitochondrial dysfunction and autophagy in nonalcoholic fatty liver disease

  CON HFD
A. General and hepatic parameters
 Initial body weight (g) 14.49 ± 0.55 14.56 ± 0.41
 Final body weight (g) 29.38 ± 5.58 43.45 ± 5.22**
 Net weight gain (g) 14.89 ± 5.60 28.89 ± 4.97**
 Liver weight (g) 1.20 ± 0.16 2.08 ± 0.47**
B. Food and Energy intake
 Dietary intake (g/day) 3.64 ± 0.37 3.66 ± 0.41
 Energy intake (kcal/day) 14.64 ± 0.68 18.29 ± 1.83**
C. Serum parameters
 TC (mM) 1.39 ± 0.16 2.98 ± 0.38**
 TG (mM) 1.64 ± 0.23 3.95 ± 0.54**
 AST (U/L) 148.14 ± 13.40 180.24 ± 10.08**
 ALT (U/L) 64.14 ± 5.56 74.84 ± 9.05*
 Blood glucose (mg/dL) 122.68 ± 12.30 174.83 ± 19.31**
 Insulin (μU/mL) 5.90 ± 1.95 26.61 ± 3.67**
D. Enzyme activity in liver
 MDA (nmol/g) 37.40 ± 7.10 74.92 ± 9.59**
 SOD (U/g) 78.92 ± 7.75 46.32 ± 6.50**
  1. Values are presented as mean ± SD (n = 6). Data were analyzed by one-way analysis ANOVA. *, ** represents significance from the control group at P < 0.05, P < 0.01