Characteristic | Severity | Mortality | ARDS | ARF | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Mild (n = 1164) | Severe (n = 684) | P | Survivor (n = 1782) | Non-survivor (n = 66) | P | No (n = 1735) | Yes (n = 113) | P | No (n = 1706) | Yes (n = 142) | P | |
Age, y | 46.22 (15.40) | 51.62 (16.99) | < 0.001 | 48.07 (16.10) | 52.09 (18.69) | 0.048 | 48.12 (16.18) | 49.79 (16.66) | 0.288 | 48.12 (16.22) | 49.41 (16.12) | 0.363 |
Male gender, n (%) | 783 (67.27) | 477 (69.74) | 0.271 | 1210 (67.90) | 50 (75.76) | 0.178 | 1175 (67.72) | 85 (75.22) | 0.097 | 1142 (66.94) | 118 (83.10) | < 0.001 |
BMI, kg/m2 | 23.43 (4.26) | 24.73 (4.52) | < 0.001 | 23.99 (4.45) | 23.07 (2.92) | 0.293 | 23.85 (4.39) | 25.44 (4.44) | 0.009 | 23.85 (4.33) | 25.51 (5.16) | 0.006 |
Comorbidities, n (%) | ||||||||||||
Hyperlipidemia | 169 (14.52) | 106 (15.50) | 0.568 | 267 (14.98) | 8 (12.12) | 0.521 | 257 (14.81) | 18 (15.93) | 0.747 | 245 (14.36) | 30 (21.13) | 0.03 |
T2DM | 85 (7.30) | 54 (7.89) | 0.641 | 134 (7.52) | 5 (7.58) | 0.986 | 130 (7.49) | 9 (7.96) | 0.854 | 135 (7.91) | 4 (2.82) | 0.013 |
Etiology, n (%) | ||||||||||||
Gallstones | 467 (40.12) | 244 (35.67) | 0.058 | 697 (39.11) | 14 (21.21) | 0.003 | 681 (39.25) | 30 (26.55) | 0.007 | 679 (39.80) | 32 (22.54) | < 0.001 |
Alcoholism | 101 (8.68) | 98 (14.33) | < 0.001 | 191 (10.72) | 8 (12.12) | 0.718 | 178 (10.26) | 21 (18.58) | 0.006 | 169 (9.91) | 30 (21.13) | < 0.001 |
Hypertriglyceridemia | 186 (15.98) | 123 (17.98) | 0.265 | 301 (16.89) | 11 (16.67) | 0.308 | 288 (16.60) | 21 (18.58) | 0.584 | 278 (16.30) | 31 (21.83) | 0.089 |
Smoker, n (%) | 337 (28.95) | 204 (29.82) | 0.691 | 525 (29.46) | 16 (24.24) | 0.36 | 505 (29.11) | 36 (31.86) | 0.533 | 490 (28.72) | 51 (35.92) | 0.07 |
Alcohol intake history, n (%) | 334 (28.69) | 257 (37.57) | < 0.001 | 568 (31.87) | 23 (34.85) | 0.611 | 540 (31.12) | 51 (45.13) | 0.002 | 520 (30.48) | 71 (50.00) | < 0.001 |
Hospital stay, d | 12.35 (8.18) | 16.56 (11.95) | < 0.001 | 14.01 (9.68) | 10.08 (14.82) | 0.042 | 13.53 (8.85) | 19.38 (19.8) | 0.003 | 13.58 (9.02) | 17.52 (17.16) | 0.009 |
Death, n (%) | 6 (0.52) | 60 (8.77) | < 0.001 | – | – | – | 29 (1.67) | 37 (32.74) | < 0.001 | 26 (1.52) | 40 (28.17) | < 0.001 |
WBC (*109/L) | 10.46 (4.96) | 14.71 (6.37) | < 0.001 | 11.94 (5.77) | 14.58 (8.26) | 0.012 | 11.84 (5.81) | 14.89 (6.36) | < 0.001 | 11.79 (5.58) | 14.92 (8.28) | < 0.001 |
Hemoglobin (g/L) | 127.61 (21.99) | 128.11 (30.90) | 0.713 | 128.26 (24.63) | 115.28 (43.57) | 0.019 | 127.78 (24.37) | 127.99 (40.63) | 0.957 | 127.78 (23.77) | 127.99 (42.19) | 0.955 |
Hematocrit | 0.46 (1.52) | 0.41 (0.52) | 0.408 | 0.45 (1.26) | 0.33 (0.10) | 0.452 | 0.45 (1.28) | 0.39 (0.15) | 0.632 | 0.45 (1.29) | 0.40 (0.23) | 0.652 |
BUN (mmol/L) | 4.70 (4.51) | 7.06 (6.74) | < 0.001 | 5.35 (5.16) | 12.37 (10.53) | < 0.001 | 5.27 (5.01) | 10.40 (9.88) | < 0.001 | 4.93 (4.32) | 13.50 (10.68) | < 0.001 |
Creatinine (μmol/L) | 77.41 (35.51) | 109.02 (99.68) | < 0.001 | 85.73 (60.61) | 191.88 (159.04) | < 0.001 | 84.88 (58.86) | 156.95 (140.72) | < 0.001 | 76.51 (28.59) | 244.83 (163.11) | < 0.001 |
Total bilirubin (μmol/L) | 38.25 (67.41) | 41.66 (52.51) | 0.277 | 38.41 (59.80) | 72.16 (107.79) | 0.023 | 39.54 (62.76) | 39.40 (53.76) | 0.983 | 39.07 (60.74) | 45.55 (79.37) | 0.274 |
Albumin (g/L) | 37.78 (7.16) | 34.19 (7.33) | < 0.001 | 36.69 (7.31) | 28.97 (7.02) | < 0.001 | 36.6.69 (7.36) | 32.31 (7.32) | < 0.001 | 36.76 (7.24) | 32.04 (8.40) | < 0.001 |
AST (IU/L) | 68.94 (113.56) | 104.17 (293.67) | 0.004 | 76.66 (121.03) | 244.29 (894.16) | 0.145 | 82.42 (206.45) | 76.95 (82.21) | 0.794 | 76.34 (120.21) | 158.44 (618.75) | 0.151 |
Calcium (mmol/L) | 2.20 (0.24) | 2.00 (0.33) | < 0.001 | 2.14 (0.27) | 1.85 (0.63) | 0.001 | 2.14 (0.27) | 1.89 (0.48) | < 0.001 | 2.14 (0.27) | 1.90 (0.44) | < 0.001 |
Blood glucose (mmol/L) | 7.41 (3.84) | 10.21 (5.37) | < 0.001 | 8.25 (4.47) | 13.33 (7.78) | 0.003 | 8.20 (4.40) | 11.54 (7.09) | 0.001 | 8.12 (4.26) | 12.59 (7.69) | < 0.001 |
LDH (IU/L) | 234.9 (104.21) | 420.76 (235.22) | < 0.001 | 305.78 (186.17) | 476.00 (326.16) | 0.003 | 298.31 (177.79) | 493.86 (291.49) | < 0.001 | 298.65 (176.75) | 475.35 (300.05) | < 0.001 |
Triglycerides (mmol/L) | 2.89 (4.37) | 4.5 (6.08) | < 0.001 | 3.51 (5.12) | 3.99 (6.52) | 0.558 | 3.38 (5.00) | 5.60 (6.88) | < 0.006 | 3.27 (4.79) | 6.7 (8.06) | < 0.001 |
CRP (mg/L) | 78.53 (58.34) | 138.28 (60.29) | < 0.001 | 109.77 (66.56) | 128.77 (62.19) | 0.036 | 106.83 (65.32) | 143.21 (66.71) | < 0.001 | 107.57 (66.88) | 134.55 (58.07) | < 0.001 |
Ranson score | 0.67 (0.77) | 2.57 (1.37) | < 0.001 | 1.34 (1.36) | 2.41 (1.58) | < 0.001 | 1.29 (1.33) | 2.64 (1.46) | < 0.001 | 1.29 (1.32) | 2.45 (1.61) | < 0.001 |
Glasgow score | 0.48 (0.69) | 2.24 (1.25) | < 0.001 | 1.09 (1.23) | 2.39 (1.53) | < 0.001 | 1.05 (1.22) | 2.45 (1.20) | < 0.001 | 1.04 (1.20) | 2.28 (1.21) | < 0.001 |
BISAP | 0.6 (0.72) | 1.95 (1.1) | < 0.001 | 1.05 (1.06) | 2.42 (1.25) | < 0.001 | 1.01 (1.04) | 2.49 (1.00) | < 0.001 | 1.00 (1.02) | 2.27 (1.20) | < 0.001 |
PASS | 105.51 (52.27) | 172.05 (81.08) | < 0.001 | 125.56 (66.82) | 253.64 (94.44) | < 0.001 | 120.82 61.05) | 273.19 (76.21) | < 0.001 | 120.73 (61.42) | 243.11 (91.49) | < 0.001 |
CSSS | 0.55 (0.78) | 2.12 (1.50) | < 0.001 | 1.08 (1.29) | 2.62 (1.69) | < 0.001 | 1.01 (1.22) | 2.98 (1.65) | < 0.001 | 0.99 (1.19) | 2.89 (1.66) | < 0.001 |