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Table 4 Multivariate analysis of factors predicting severity, mortality, ARDS, and ARF in AP

From: Accuracy of conventional and novel scoring systems in predicting severity and outcomes of acute pancreatitis: a retrospective study

Characteristic Severity Mortality ARDS ARF
OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P
Age 0.994 (0.975–1.014) 0.575 1.023 (0.97–-1.069) 0.308 – – – –
Male gender – – – – – – 0.731 (0.101–5.295) 0.731
BMI, kg/m2 0.985 (0.919–1.055) 0.66 – – 1.139 (1.022–1.271) 0.019 1.125 (0.996–1.269) 0.057
Etiology         
 Gallstones 1.256 (0.635–2.487) 0.512 0.255 (0.036–1.826) 0.174 1.794 (0.620–5.193) 0.281 0.974 (0.197–4.821) 0.974
 Alcoholism 1.416 (0.526–3.808) 0.491 – – 0.378 (0.074–1.923) 0.241 0.844 (0.153–4.649) 0.846
 Hypertriglyceridemia        0.365 (0.065–2.036) 0.25
Smoker        0.996 (0.285–3.488) 0.995
Alcohol intake history 0.862 (0.467–1.590) 0.634 – – 1.956 (0.657–5.827) 0.228 3.613 (0.810–16.122) 0.092
Comorbidities
 Hyperlipidemia – – – – – – 1.501 (0.529–4.26) 0.446
 T2DM – – – – – – 0.999 (0.363–2.749) 0.998
WBC (*109/L) 1.110 (1.040–1.184) 0.002 0.946 (0.819–1.094) 0.456 1.135 (1.048–1.23) 0.002 0.946 (0.839–1.067) 0.368
Hemoglobin (g/L) – – 1.023 (0.994–1.052) 0.118 – – – –
BUN (mmol/L) 1.124 (0.974–1.297) 0.109 1.013 (0.914–1.122) 0.808 0.99 (0.917–1.069) 0.802 1.243 (1.097–1.408) 0.001
Creatinine (μmol/L) 1.005 (0.996–1.015) 0.268 1.006 (0.999–1.013) 0.105 1.002 (0.996–1.009) 0.484 – –
Total bilirubin (μmol/L) – – 1.013 (1.004–1.023) 0.007 – – – –
Albumin (g/L) 0.940 (0.894–0.989) 0.016 0.948 (0.833–1.079) 0.418 1.035 (0.978–1.095) 0.234 0.939 (0.854–1.032) 0.191
AST (IU/L) 1.002 (0.999–1.006) 0.18 – – – – – –
Calcium (mmol/L) 0.196 (0.065–0.592) 0.004 0.882 (0.089–8.692) 0.914 0.042 (0.006–0.303) 0.002 1.205 (0.313–4.639) 0.786
Blood glucose (mmol/L) 1.081 (1.016–1.150) 0.014 1.023 (0.916–1.143) 0.686 1.021 (0.938–1.112) 0.624 1.054 (0.956–1.162) 0.294
LDH (IU/L) 1.004 (1.002–1.006) < 0.001 1.003 (1.000–1.005) 0.061 1.000 (0.998–1.002) 0.785 1.000 (0.998–1.003) 0.781
Triglycerides (mmol/L) 1.022 (0.961–1.086) 0.486 – – 0.943 (0.845–1.051) 0.287 1.119 (1.012–1.239) 0.029
CRP (mg/L) 1.007 (1.003–1.012) 0.002 0.999 (0.988–1.011) 0.844 1.002 (0.995–1.008) 0.409 1.000 (0.993–1.008) 0.926
  1. ARDS Acute respiratory distress syndrome, ARF Acute renal failure, AP acute pancreatitis, BMI Body-mass index, T2DM Type-2 diabetes mellitus, CRP C-reactive protein, AST Aspartate transaminase, BUN Blood urea nitrogen, LDH Lactate dehydrogenase, BISAP Bedside index of severity in acute pancreatitis, PASS Pancreatic activity scoring system, CSSS Chinese simple scoring system, WBC White blood cell count, OR Odds ratio, CI Confidence interval. P < 0.05 was accepted as statistically significant
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Lipids in Health and Disease

ISSN: 1476-511X