Effect of statins on post-contrast acute kidney injury: a multicenter retrospective observational study

Table 3 Univariate and multivariate linear association for Percentage of elevated creatinine among the whole population

	Univariable Analysis			Multivariable Analysis
	B	β	P	B	β	P
Male	−1.973	−0.024	0.109
Age	0.234	0.065	<0.001	0.238	0.068	<0.001
Smoking	−2.232	−0.022	0.151
Drinking	−3.535	−0.033	0.029	−1.56	−0.015	0.353
Hypertension	−0.909	−0.011	0.454
Diabetes	3.007	0.033	0.028	2.824	0.032	0.045
eGFR	−0.027	−0.016	0.286
Uric acid	0.003	0.009	0.562
LDL-C	−0.335	− 0.008	0.603
CRP	0.224	0.13	<0.001	0.176	0.106	<0.001
LVEF	−0.345	− 0.117	<0.001	−0.294	− 0.102	<0.001
Excess volumes of CM	6.616	0.036	0.022	4.567	0.025	0.11
Iso-osmolar CM	−0.027	0	0.983
Contrast Volume	−0.002	− 0.003	0.834
Pre-operative statin therapy	−11.39	−0.11	<0.001	−12.06	−0.118	<0.001
Prior myocardial infarction	−0.733	−0.002	0.874
Prior PCI	−1.948	−0.011	0.457
Prior CABG	−8.818	−0.013	0.378
Prior cardiac surgery (except CABG)	2.18	0.003	0.827
Angiography combined with PCI	−0.978	− 0.013	0.406
Multi vessel PCI	−1.287	−0.019	0.416
Total length of stents	0.001	0.001	0.972

Abbreviations: PC-AKI post-contrast acute kidney injury, eGFR estimated glomerular filtration rate, LDL-C low-density lipoprotein cholesterol, CRP C-reactive protein, LVEF left ventricular ejection fractions, CM contrast medium, ACEI angiotensin converting enzyme inhibitors, PCI percutaneous coronary intervention, CABG coronary artery bypass grafting

ISSN: 1476-511X