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Table 1 Gut microbiota differences in obese human and rodent cohorts, preoperative bariatric dietary cohort, post-bariatric surgery human and rodent cohorts, post-allogenic FMT cohort

From: A review on gut microbiota: a central factor in the pathophysiology of obesity

Cohort

Microbiota Findings

Obese cohort [10, 11, 22, 29,30,31,32]

↓ Rikenellaceae and Christensenellaceae

↓ Bifidobacterium, Oscillospira and Akkermansia

Obese cohort [33]

↓ Alistipes finegoldii and Alistipes senegalensis

Obese cohort [34]

Alistipes = marker of persistent weight loss success

Obese cohort [11, 35]

↓ Faecali prausnitzii

Obese cohort [21, 32, 36]

Weight loss ↑ Faecali prausnitzii, Akkermansia and Christensenellaceae

Obese cohort [37]

↑ Prevotellaceae, Coriobacteriaceae, Erysipelotrichaceae, and Alcaligenaceae

Elevated BMI [38, 39]

↑ Roseburia

Obese cohort [40]

↑ Eubacterium dolichum

Obese cohort [37]

↑ H2-producing bacteria; (Prevotellaceae, certain groups within the Firmicutes and Archaea)

Obese cohort [11, 26]

↑ gram-negative microbes

↑ Fusobacterium, Escherichia-Shigella, Pseudomonas and Campylobacter

Obese children and overweight women [30, 41]

↑ Staphylococcus aureus

Obese cohort on preoperative diet [42]

↓ Streptococcaceae and Ruminococcaceae

↑ Rikenellaceae and Bifidobacteriaceae

Post-bariatric surgery [37, 42, 43]

↑ Gammaproteobacteria (Enterobacteriaceae)

↓ Firmicutes (Clostridium difficile, Clostridium hiranonis, and Gemella sanguinis)

↓ methanogens

Post-bariatric surgery [43, 44]

↑ Escherichia, Klebsiella, and Pseudomonas

Six months post-bariatric surgery [42]

↑ Streptococcaceae and Veillonellaceae

↓ Bifidobacteriaceae

Rodent model – post bariatric surgery [45]

↑ Bacteroidetes, Verrucomicrobia, and Proteobacteria

↑ Alistipes, Akkermansia, and Escherichia

Rodent model – post bariatric surgery [46]

↑ Proteobacteria (Enterobacter hormaechei)

↓ Firmicutes and Bacteroidetes

Allogenic FMT recipients [47]

↑ Roseburia intestinalis