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Table 4 Univariate and multivariate Cox proportional hazards model analysis for disease-free survival

From: Prognostic significance of preoperative serum triglycerides and high-density lipoproteins cholesterol in patients with non-small cell lung cancer: a retrospective study

Characteristics

Univariate analysis

Multivariate analysis

HR

95%CI

P value

HR

95%CI

P value

Age

  

0.050

   

  ≤ 57

1.000

Reference

    

 >57

1.323

1.000–1.751

    

Gender

  

0.021

  

0.008

 Male

1.000

Reference

 

1.000

Reference

 

 Female

0.704

0.522–0.948

 

0.664

0.491–0.898

 

Smoking history

  

0.270

   

 Y

1.000

Reference

    

 N

0.856

0.649–1.128

    

Stage

  

<0.001

  

0.001

 I-II

1.000

Reference

 

1.000

Reference

 

 IIIA

4.100

3.132–5.367

 

2.367

1.433–3.909

 

Pathological tumor

      

Classification (pT)

  

0.001

  

0.577

 pT1–2

1.000

Reference

 

1.000

Reference

 

 pT3–4

1.726

1.234–2.415

 

1.124

0.746–1.694

 

Pathological lymph node

      

stage (pN)

  

<0.001

  

<0.001

 pN0

1.000

Reference

 

1.000

Reference

 

 pN1–2

4.507

3.368–6.032

 

5.174

3.122–8.575

 

Histological type

  

0.248

   

 Squamous cell carcinoma

1.000

Reference

    

 Adenocarcinoma

0.902

0.677–1.203

    

 Large cell carcinoma

1.315

0.815–2.122

    

Surgery type

  

<0.001

  

0.082

 Lobectomy

1.000

Reference

 

1.000

Reference

 

 Pneumonectomy

2.874

2.166–3.814

 

1.392

0.915–2.118

 

 Other

2.173

1.341–3.519

 

0.827

0.472–1.449

 

Adjuvant chemotherapy

  

<0.001

  

<0.001

 Y

1.000

Reference

 

1.000

Reference

 

 N

2.605

1.960–3.462

 

3.050

1.723–5.397

 

GLU (mmol/L)

  

0.357

   

  ≤ 5.75

1.000

Reference

    

 >5.75

0.873

0.654–1.166

    

TC (mmol/L)

  

0.779

   

  ≤ 4.59

1.000

Reference

    

 >4.59

0.962

0.733–1.263

    

TG (mmol/L)

  

<0.001

  

0.002

  ≤ 1.21

1.000

Reference

 

1.000

Reference

 

 >1.21

1.876

1.444–2.436

 

1.544

1.177–2.025

 

HDL-C (mmol/L)

  

<0.001

  

<0.001

  ≤ 1.26

1.000

Reference

 

1.000

Reference

 

 >1.26

0.496

0.372–0.661

 

0.593

0.444–0.793

 

LDL-C (mmol/L)

  

0.027

  

0.565

  ≤ 2.26

1.000

Reference

 

1.000

Reference

 

 >2.26

1.384

1.038–1.845

 

1.091

0.810–1.470

 

ApoA1(g/L)

  

0.390

   

  ≤ 1.21

1.000

Reference

    

 >1.21

0.890

0.682–1.161

    

ApoB(g/L)

  

0.126

   

  ≤ 1.15

1.000

Reference

    

 >1.15

0.704

0.449–1.103

    

Lpa (mg/L)

  

0.344

   

  ≤ 53

1.000

Reference

    

 >53

0.839

0.582–1.207

    
  1. Data were analyzed by Cox proportional hazards model. P < 0.05 was considered significant