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Table 2 Association between HDL-C and BMD

From: High-density Lipoprotein Cholesterol Is Negatively Correlated with Bone Mineral Density and Has Potential Predictive Value for Bone Loss

 

Model 1

β (95% CI) P value

Model 2

β (95% CI) P value

Model 3

β (95% CI) P value

Total femur BMD

-0.0023 (-0.0025, -0.0021) <0.000001

-0.0013 (-0.0015, -0.0011) <0.000001

-0.0004 (-0.0006, -0.0002) 0.000668

Femur neck BMD

-0.0017 (-0.0019, -0.0015) <0.000001

-0.0011 (-0.0013, -0.0009) <0.000001

-0.0003 (-0.0005, -0.0001) 0.004985

Trochanter BMD

-0.0016 (-0.0018, -0.0014) <0.000001

-0.0008 (-0.0010, -0.0007) <0.000001

-0.0002 (-0.0004, -0.0001) 0.012022

Intertrochanter BMD

-0.0027 (-0.0029, -0.0024) <0.000001

-0.0016 (-0.0018, -0.0013) <0.000001

-0.0005 (-0.0007, -0.0002) 0.000301

Total spine BMD

-0.0010 (-0.0012, -0.0008) <0.000001

-0.0010 (-0.0012, -0.0008) <0.000001

-0.0004 (-0.0006, -0.0002) 0.001002

L1 BMD

-0.0016 (-0.0018, -0.0014) <0.000001

-0.0012 (-0.0014, -0.0009) <0.000001

-0.0005 (-0.0007, -0.0002) 0.000112

L2 BMD

-0.0012 (-0.0014, -0.0010) <0.000001

-0.0011 (-0.0013, -0.0009) <0.000001

-0.0005 (-0.0007, -0.0003) 0.000030

L3 BMD

-0.0007 (-0.0009, -0.0005) <0.000001

-0.0009 (-0.0011, -0.0007) <0.000001

-0.0003 (-0.0006, -0.0001) 0.005108

L4 BMD

-0.0006 (-0.0008, -0.0004) <0.000001

-0.0008 (-0.0010, -0.0006) <0.000001

-0.0002 (-0.0005, -0.0000) 0.049655

  1. Model 1: no covariates were adjusted. Model 2: age (20-29, 30-39, 40-49; 50-59; ≥60), sex (male; female), race/ethnicity (Mexican American; other Hispanic; non-Hispanic white; non-Hispanic black; other races) were adjusted. Model 3: age (20-29, 30-39, 40-49; 50-59; ≥60), sex (male; female), race/ethnicity (Mexican American; other Hispanic; non-Hispanic white; non-Hispanic black; other races), education level (under high school; high school or equivalent; above high school), income to poverty ratio (quartile groups), BMI (obese, overweight, normal), smoking status (less than 100 cigarettes; greater than or equal to 100 cigarettes), alcohol consumption status (had at least 12 alcohol drinks past one year; have less than 12 alcohol drinks past one year), hypertension (yes; no), diabetes (yes; no; borderline), ALT (quartile groups), AST (quartile groups), total calcium (quartile groups), cholesterol (quartile groups), and C-reactive protein (quartile groups) were adjusted. HDL-C high-density lipoprotein cholesterol; BMD bone mineral density; ALT alanine aminotransferase; AST aspartate aminotransferase
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Lipids in Health and Disease

ISSN: 1476-511X