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Table 3 Adjusted hazard ratios (95% confidence interval) of T2DM incidence conforming to baseline levels of HDL-C

From: Association between high-density lipoprotein cholesterol and type 2 diabetes mellitus among Chinese: the Beijing longitudinal study of aging

Model

HDL-C (mmol/L)

P value

< 1.15

1.15–1.39

1.40–1.69

≥ 1.70

Cox regression

 I

1.00

0.76 (0.49–1.19)

0.44 (0.26–0.76)

0.39 (0.23–0.67)

< 0.001

 II

1.00

0.80 (0.51–1.25)

0.49 (0.29–0.84)

0.44 (0.25–0.77)

0.002

 III

1.00

0.79 (0.51–1.25)

0.54 (0.31–0.94)

0.48 (0.27–0.84)

0.008

 IV

1.00

0.75 (0.48–1.18)

0.49 (0.28–0.85)

0.44 (0.25–0.77)

0.004

Fine-Gray model

 I

1.00

0.77 (0.50–1.19)

0.43 (0.26–0.72)

0.39 (0.23–0.67)

< 0.001

 II

1.00

0.82 (0.53–1.26)

0.47 (0.28–0.80)

0.45 (0.27–0.78)

0.003

 III

1.00

0.82 (0.53–1.27)

0.53 (0.31–0.90)

0.49 (0.29–0.85)

0.009

 IV

1.00

0.78 (0.50–1.22)

0.48 (0.28–0.82)

0.46 (0.27–0.79)

0.005

  1. BMI, body mass index; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglycerides
  2. I: Adjustments were made for gender, age, education, smoking status, alcohol intake, regular exercise, residence and job type
  3. II: Model I along with hypertension, BMI, consumptions of staple foods and eggs
  4. III: Model II along with LDL-C, TG, antihypertensive drug and cardiovascular medication
  5. IV: Model III along with FPG