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Table 3 Multivariable regression analysis of serum LDL-C levels and current MetS, by inflection points

From: Association between serum low-density lipoprotein cholesterol and metabolic syndrome in a working population

Inflection points of LDL-C (mg/dL) Odds Ratio (95% Confidence Interval) P-value
Crude Model Ia Model IIb
Total (n = 60,799)
  < 113.6 Ref. Ref. Ref.
  ≥ 113.6 1.66 (1.56, 1.76) < 0.001 1.09 (1.02, 1.16) 0.010 1.09 (1.01, 1.17) 0.019
Men (n = 34,827)
  < 117.6 Ref. Ref. Ref.
  ≥ 117.6 1.45 (1.35, 1.55) < 0.001 1.02 (0.95, 1.10) 0.551 1.05 (0.97, 1.15) 0.212
Women (n = 25,972)
  < 135.0 Ref. Ref. Ref.
  ≥ 135.0 2.66 (2.38, 2.96) < 0.001 1.53 (1.36, 1.72) < 0.001 1.55 (1.36, 1.77) < 0.001
  1. aModel I adjust for age
  2. bModel II adjust for gender, age, BMI, DBP, ABSI, and smoking, if not be stratified
  3. LDL-C low-density lipoprotein cholesterol, MetS metabolic syndrome, BMI body mass index, DBP diastolic blood pressure, ABSI a body shape index