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Table 6 Significant associations between rs28365927 A Carriers(AA+AG) and Clinical Characteristics in a covariate adjusted linear regression analysis in the NAFLD Populationa

From: Sirtuin3 rs28365927 functional variant confers to the high risk of non-alcoholic fatty liver disease in Chinese Han population

Characteristic β-coefficient STAT P Value
BMI, kg/m2 −0.569 −1.506 0.133
SBP, mmHg −3.082 −1.117 0.265
DBP, mmHg −2.583 −1.196 0.233
WC, cm −0.440 −0.373 0.709
HP, cm −1.148 −1.196 0.233
TP,g/L 0.116 0.185 0.853
Albumin,g/L 0.060 0.106 0.915
Globulin,g/L −0.424 −0.558 0.577
A/G 0.039 0.897 0.370
TBIL, umol/L 1.220 1.511 0.132
DBIL, umol/L 0.703 1.542 0.124
TBA,umol/L 0.154 0.156 0.876
ALT, U/L 7.632 2.013 0.045
AST, U/L 2.446 0.857 0.393
FBG, mmol/L 0.025 0.130 0.897
LDL-C, mmol/L −0.101 −0.903 0.367
TG, mmol/L −0.437 −1.968 0.050
TC, mmol/L −0.019 −0.135 0.893
HDL-C, mmol/L −0.003 −0.080 0.936
  1. Abbreviations: BMI Body Mass Index, SBP systemic blood pressure, DBP diastolic blood pressure, WC Waist circumference, HP Hip circumference, TP Total Protein, A/G the ratio of albumin to globulin, TBIL total bilirubin, DBIL direct bilirubin, TBA total bile acid, ALT glutamic-pyruvic transaminase, AST glutamic oxalacetic transaminase, FBG fasting blood-glucose, LDL-C low density lipoprotein cholesterin, TG triglyceride, TC total cholesterol, HDL-C high density lipoprotein cholesterol, NAFLD nonalcoholic fatty liver disease
  2. aβ-coefficient: estimated quantitative effect of rs28365927 A Carriers on a phenotype of NAFLD, STAT: T statistic, P: level of statistical significance of the covariate(age and gender) adjusted linear regression analysis. P-value<0.05 considered as statistically significant (in bold)