Retinol-binding protein 4 in combination with lipids to predict the regression phenomenon of autism spectrum disorders

Table 1 Characteristics of the participants

Variables	ASD	Control	P value	ASD(n = 60)		P value
Variables	(n = 60)	(n = 36)	P value	with regression	without regression	P value
Age(years)	7.27 ± 3.21	7.28 ± 3.12	0.987	7.56 ± 3.36	7.14 ± 3.17	0.65
Gender(male/female)	39/21	24/12	0.778	11/7	29/13	0.55
BMI	15.58 ± 1.17	15.32 ± 1.16	0.304	15.35 ± 0.07	16.50 ± 0.42	0.063
CARS	38.83 ± 8.25	16.00 ± 3.83	0	38.33 ± 9.13	39.05 ± 7.94	0.761
TG (mmol/l)	1.07 ± 0.30	1.10 ± 0.27	0.584	0.92 ± 0.18	1.13 ± 0.32	0.01
TC (mmol/l)	2.83 ± 0.48	3.08 ± 0.35	0.007	2.75 ± 0.46	2.87 ± 0.49	0.375
HDL-C(mmol/l)	1.10 ± 0.21	1.18 ± 0.12	0.027	1.02 ± 0.18	1.13 ± 0.22	0.088
LDL-C(mmol/l)	1.62 ± 0.35	1.68 ± 0.34	0.374	1.52 ± 0.35	1.66 ± 0.35	0.175
TG/TC	0.38 ± 0.12	0.36 ± 0.77	0.221	0.34 ± 0.79	0.40 ± 0.12	0.052
TG/HDLC	1.02 ± 0.40	0.93 ± 0.22	0.222	0.93 ± 0.27	1.06 ± 0.43	0.237
TG/LDLC	0.69 ± 0.25	0.67 ± 0.16	0.602	0.64 ± 0.23	0.71 ± 0.25	0.317
TC/HDLC	2.69 ± 0.74	2.62 ± 0.25	0.575	2.78 ± 0.77	2.65 ± 0.73	0.512
TC/LDLC	1.79 ± 0.28	1.87 ± 0.23	0.169	1.85 ± 2.69	1.77 ± 2.91	0.348
RBP4(ug/ml)	20.31 ± 2.79	22.56 ± 3.40	0.001	18.81 ± 1.99	21.08 ± 2.81	0.001

Variables are presented as mean ± standard deviation. P-values were derived from the independent sample t-test, Mann-Whitney U test, or χ2 test
ASD autism spectrum disorders, RBP4 retinol-binding protein 4, TC cholesterol, HDLC high-density lipoprotein, LDLC low–density lipoprotein, TG triglyceride, CARS Childhood Autism Rating Scale, ADI-R Autism Diagnostic Interview-Revised, ASD-R autism spectrum disorders with regression, ASD-NR autism spectrum disorders without regression, ELISA enzyme-linked immunosorbent assay, BMI Body Mass Index

ISSN: 1476-511X