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Fig. 5 | Lipids in Health and Disease

Fig. 5

From: Serum lipids are associated with nonalcoholic fatty liver disease: a pilot case-control study in Mexico

Fig. 5

Receiver Operator Characteristic (ROC) curves of the top 10 lipids and other models

Sensitivity (ability of panel to correctly identify NAFLD cases) and 1-specificity (ability of test to correctly identify healthy controls) are plotted. Area under the ROC curve (AUROC) is the predictive power of the panel to differentiate cases from controls. Perfect prediction would result in an AUROC of 1.0; random chance corresponds with an AUROC of 0.50. The top ten lipid species alone, as determined from the random forest analysis, are better predictors of NAFLD than models that include age, sex, BMI, PNPLA3 genotype, diabetes, and/or metabolic syndrome (MetS). Abbreviations: AUROC area under the ROC curve, BMI body mass index MetS metabolic syndrome, NAFLD nonalcoholic fatty liver disease, ROC Receiver Operator Characteristic

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